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首页> 外文期刊>Journal of obstetrics and gynaecology: the journal of the Institute of Obstetrics and Gynaecology >First trimester 3D ultrasound placental volume for predicting preeclampsia and/or intrauterine growth restriction
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First trimester 3D ultrasound placental volume for predicting preeclampsia and/or intrauterine growth restriction

机译：用于预测先兆子痫和/或宫内生长限制的第一个三个月3D超声胎盘体积

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The objective of the study was to determine the sensitivity of the placental volume for predicting preeclampsia and/or intrauterine growth restriction (IUGR) in the first trimester. A prospective observational study was conducted in pregnant women with a gestational age of 11 to 13(+6)weeks. A 3D transabdominal placental volume measurement was performed at the time of first-trimester aneuploidy screening. The predictive values of this test were calculated. The data from 360 pregnant women was analysed. Seventeen cases developed preeclampsia and/or IUGR. The 10(th) percentile of placental volume was used as the cut-off level. The sensitivity, specificity, positive predictive value and negative predictive value of placental volume less than the 10(th) percentile for prediction of preeclampsia and/or IUGR were 23.5%, 90.7%, 11.1% and 96%, respectively. The sensitivity, specificity, positive predictive value and negative predictive value for prediction of early onset preeclampsia were 50%, 90.7%, 3.0% and 99.7%, respectively. This study demonstrated that the placental volume was lower in the cases with preeclampsia and/or IUGR. It was not an effective screening tool for preeclampsia and/or IUGR in the first trimester.IMPACT STATEMENTWhat is already known on this subject? Placental volume may reflect trophoblast invasion, but much earlier, in the first trimester. The estimation of a smaller early placental volume has been shown to be significantly associated with preeclampsia and IUGR.What do the results of this study add? The placental volume was lower in the cases with preeclampsia and/or IUGR. It was not an effective screening tool for preeclampsia and/or IUGR in the first trimester. But it might be used for predicting early onset preeclampsia.What are the implications of these findings for clinical practice and/or further research? Further research of placental volume in the first trimester for predicting an early onset preeclampsia should be conducted.
机译：该研究的目的是确定胎盘体积的敏感性，以预测前三个月的先兆子痫和/或宫内生长限制（IUGR）。在孕妇的孕妇中进行了一个预期的观察研究，其妊娠期11至13岁（+ 6）周。在孕孕前三个间倍差筛选时进行3D天腹胎盘体积测量。计算该测试的预测值。分析了360名孕妇的数据。十七个病例开发出预口化和/或IUGR。胎盘体积的10（Th）百分位用作截止水平。胎盘体积的敏感性，特异性，阳性预测值和负预测值小于预测和/或IUGR预测的10（Th）百分位分别为23.5％，90.7％，11.1％和96％。预测早期发病预膜上预测的敏感性，特异性，阳性预测值和负预测值分别为50％，90.7％，3.0％和99.7％。本研究表明，胎盘体积在患有预胰抗和/或IUGR的情况下较低。它不是Preclampsia和/或IUGR中的有效筛查工具在第一个春季赛段.Impact声明在这个主题上已经知道了什么？胎盘体积可能反映孕产妇入侵，但早些时候在第一个三个月中。已经显示出较小的早期胎盘体积的估计与Preclampsia和Iugr显着相关。本研究的结果添加了什么？胎盘体积在胎儿胰腺炎和/或IUGR病例中较低。它不是前三个月的预贷方和/或IUGR的有效筛查工具。但它可能用于预测早期发作前普拉明士。这些发现对临床实践和/或进一步研究的影响是什么？进一步研究胎盘体积在妊娠早期预测早期发病预痫的胎儿体积。

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