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首页> 外文期刊>Journal of obstetrics and gynaecology: the journal of the Institute of Obstetrics and Gynaecology >Adrenal disorders in pregnancy, labour and postpartum - an overview
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Adrenal disorders in pregnancy, labour and postpartum - an overview

机译：怀孕，劳动和产后的肾上腺障碍 - 概述

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摘要

Adrenal disorders may manifest during pregnancy for the first time, or present from before pregnancy as either undiagnosed or diagnosed and treated. They may present as hormonal hypofunction or hyperfunction, or with mass effects or other non-endocrine effects. Adrenal disorders such as Cushing's syndrome, Addison's disease, pheochromocytoma, primary hyper-aldosteronism and adreno-cortical carcinoma are rare in pregnancy. Pregnancy presents special problems in the evaluation of the hypothalamic-pituitary-adrenal and renin-angiotensin-aldosterone axis as these undergoe major changes during pregnancy. Diagnosis is challenging as symptoms associated with pregnancy are also seen in adrenal diseases. A timely diagnosis and treatment is critical as these disorders can cause maternal and foetal morbidity and mortality. A high index of suspicion must be maintained as they can go unrecognised and untreated. An early diagnosis and treatment often improves outcomes. The aim of this article is to review the patho-physiology, clinical manifestation, diagnosis and management of various adrenal disorders during pregnancy.
机译：肾上腺疾病在怀孕期间第一次表现出，或者在怀孕之前作为未确诊或诊断和治疗。它们可以作为荷尔蒙的脾功能紊乱或高障碍，或者具有大规模效果或其他非内分泌效应。肾上腺疾病如缓冲的综合征，Addison疾病，嗜铬细胞瘤，原发性高醛和肾上腺细胞和肾上腺皮质癌怀孕罕见。怀孕呈现出对丘脑垂体 - 肾上腺和肾素 - 血管紧张素 - 醛固酮轴的评价特殊问题，因为这些妊娠期间的重大变化。由于肾上腺疾病也观察到与妊娠有关的症状，诊断是具有挑战性的。当这些疾病会导致母体和胎儿发病率和死亡率时，及时诊断和治疗至关重要。必须保持高度怀疑，因为它们可以无法识别和未经治疗。早期诊断和治疗通常会改善结果。本文的目的是审查妊娠期间各种肾上腺疾病的病理生理学，临床表现，诊断和管理。

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