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首页> 外文期刊>Journal of neurology >Diagnostic accuracy of a smartphone bedside test to assess the fixation suppression of the vestibulo-ocular reflex: when nothing else matters
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Diagnostic accuracy of a smartphone bedside test to assess the fixation suppression of the vestibulo-ocular reflex: when nothing else matters

机译：智能手机床头检测的诊断准确性评估前毒镜 - 眼睛反射的固定抑制：无论什么都不重要

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Objective Validation of a bedside test to objectify the fixation suppression of the vestibulo-ocular reflex (FS-VOR) in patients with a cerebellar syndrome and healthy controls. Methods The vestibulo-ocular reflex and its fixation suppression were assessed by video-nystagmography (VNG) in 20 healthy subjects (mean age 56 +/- 15) and 19 patients with a cerebellar syndrome (mean age 70 +/- 11). The statistical cutoff delineating normal from pathological FS-VOR was determined at the 2.5th percentile of the normal distribution of the healthy cohort. VNG was then compared to a bedside test, where eye movements were recorded with a smartphone while patients were rotated on a swivel chair at a defined speed and amplitude. These videos were rated as normal or pathological FS-VOR by six blinded raters, and results compared to VNG. Results VNG in healthy controls showed FS-VOR with a reduction of nystagmus beats by 95.0% +/- 7.2 (mean +/- SD). The statistical cutoff was set at 80.6%. Cerebellar patients reduced nystagmus beats by only 26.3% +/- 25.1. Inter-rater agreement of the smartphone video ratings was 85%. The sensitivity of the video ratings to detect an impaired FS-VOR was 99%, its specificity 92%. Inter-test agreement was 91%. Conclusion The smartphone bedside test is an easily performed, reliable, sensitive, specific, and inexpensive alternative for assessing FS-VOR.
机译：客观验证床头率测试，以了解小脑综合征和健康对照中的患者前院反射（FS-VOR）的固定抑制。方法采用video-nystagmography（vng）在20个健康受试者（平均56 +/-15）和19例患有小脑综合征（平均70 +/- 11）的患者的患者中评估前纤维眼反射及其固定抑制。从病理FS-VOR中划定正常的统计截止在健康队列正常分布的2.5百分位数中确定。然后将VNG与床头检测进行比较，其中用智能手机记录眼部运动，同时患者以定义的速度和幅度在旋转椅上旋转。这些视频被六个盲化评估者的正常或病理FS-VOR评为，结果与VNG相比。结果健康对照中的v通道显示FS-VOR，减少了95.0％+/- 7.2（平均+/- SD）。统计截止值设定为80.6％。小脑患者只需26.3％+/- 25.1即可减少眼球菌率。智能手机视频评级的帧间协议为85％。检测受损FS-VOR的视频额定值的灵敏度为99％，其特异性为92％。测试间协议是91％。结论智能手机床头段测试是一种易于执行，可靠，敏感，具体，廉价的替代品，用于评估FS-VOR。

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