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首页> 外文期刊>Journal of neurology >Striatal hand In Parkinson's diseases the re-evaluatlon of an old clinical sign
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Striatal hand In Parkinson's diseases the re-evaluatlon of an old clinical sign

机译：帕金森的脊椎疾病疾病的重新评估旧临床标志

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Among postural abnormalities in Parkinson's disease (PD), striatal hand (SH) is a particularly underex-plored phenomenon. It leads to extreme abnormalities of hand posture, causing altered dexterity, pain and disfigurement. In our study, three blinded investigators examined several pictures of the hands of individuals with PD (N = 40) and controls (N = 15). The investigators quantified postural alterations using the Striatal Hand Score. Demographic and clinical data were also collected. As no differences were detected among investigators agreement, a final Hand Score (HS, range 0-4) was obtained for each hand. The Striatal Hand Score in both the left and right hand was significantly different in PD compared to controls (p < 0.001 for both left and right hand). Striatal hand was significantly worse on the side of PD onset, and on the side with greater PD symptomatology. The finding of a striatal hand was 100 % specific for a diagnosis of PD. Nine PD subjects were evaluated both on and off medication, and dopaminergic treatment did not significantly change the Striatal Hand Score. Our findings suggest that in patients without any explanation for hand deformities other than PD, striatal hand occurs very often, and is highly specific for the side of worst PD involvement. We recommend including an evaluation for SH as part of routine practice. This study emphasizes the importance of a careful observation of the patient in order to improve diagnostic accuracy.
机译：在帕金森病（Pd）的姿势异常中，纹纹身手（SH）是一个特别是缺陷的缺陷现象。它导致手动姿势的极度异常，导致灵巧，疼痛和毁容发生了改变。在我们的研究中，三个盲目的调查人员检查了具有PD（n = 40）和对照（n = 15）的个体手中的几张图片。调查人员使用纹纹身分数量化姿势改变。收集人口统计和临床数据。由于调查人员协议中未检测到差异，因此每只手获得最终的手数（HS，范围0-4）。与对照相比，Pd中左侧和右手双手的纹纹手比得分显着不同（左手和右手的P <0.001）。 PD发作侧面的纹纹身手显着差，并在较大的PD症状学侧面。尖端手的发现是诊断PD的100％特异性。九种PD受试者被评估，既开启和关药，多巴胺能治疗没有显着改变纹纹身手数。我们的研究结果表明，在没有任何解释除Pd以外的手畸形的患者中，纹纹手均经常发生，并且对于最差Pd受累的一侧具有高度特异性。我们建议将SH的评估包括为常规实践的一部分。这项研究强调了仔细观察患者以提高诊断准确性的重要性。

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