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首页> 外文期刊>Journal of neurology >An eye-tracker controlled cognitive battery: overcoming verbal-motor limitations in ALS
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An eye-tracker controlled cognitive battery: overcoming verbal-motor limitations in ALS

机译：一种眼睛跟踪控制的认知电池：克服ALS的言语电机限制

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We assessed language, attention, executive, and social cognition abilities in a sample of patients with Amyotrophic Lateral Sclerosis (ALS) by means of a recently developed cognitive battery based on oculomotor control with eye-tracking (ET) technology. Twenty-one ALS patients and 21 age- and education-matched healthy subjects underwent the ET-based cognitive assessment, together with the standard cognitive screening tools [Frontal Assessment Battery (FAB); Montreal Cognitive Assessment (MoCA); and Digit Sequencing Task]. Psychological measures of anxiety (State-Trait Anxiety Inventory-Y) and depression (Beck Depression Inventory) were also collected, and an ET usability questionnaire was administered. For patients, clinical and respiratory examinations were also performed, together with behavioural assessment (Frontal Behavioural Inventory). The developed battery discriminated among patients and controls with regard to measures of verbal fluency, frontal abilities, and social cognition. Measures of diagnostic utility confirmed a higher diagnostic accuracy of such ET-based tests with respect to FAB; similar diagnostic accuracy emerged when comparing them to the other standard cognitive tools (MoCA, WM). Usability ratings about the ET tests were comparable among the two groups. The ET-based neuropsychological battery demonstrated good levels of diagnostic accuracy and usability in a clinical population of non-demented ALS patients, compared to matched healthy controls. Future studies will be aimed at further investigate validity and usability components by recruiting larger sample of patients, both in moderate-to-severe stages of the disease and affected by more severe cognitive impairment.
机译：通过基于眼动脉控制（ET）技术的动血管控制，我们通过最近开发的认知电池评估了肌萎缩侧面硬化剂（ALS）样本中的语言，关注，行政和社会认知能力。二十一体患者和21例年龄和教育匹配的健康受试者接受了基于ET的认知评估，以及标准认知筛查工具[正面评估电池（Fab）;蒙特利尔认知评估（MOCA）;和数字测序任务]。还收集了焦虑的心理措施（国家特质焦虑症-Y）和抑郁症（Beck抑郁库存），并管理了ET可用问卷。对于患者，还进行临床和呼吸检查，以及行为评估（正面行为库存）。关于患者的开发电池在患者中歧视，并对言语流利，正面能力和社会认知的措施进行控制。诊断效用的测量证实了相对于FAB的基于ET的测试的诊断准确性更高;在将它们与其他标准认知工具（MOCA，WM）进行比较时出现了类似的诊断准确性。关于ET测试的可用性评级在两组中具有相当的。与匹配的健康对照相比，ET基神经心理电池在临床群体中展示了临床群体的诊断准确性和可用性。未来的研究将通过募集患者的更大样本，以进一步调查有效性和可用性组分，既可疾病中度至严重的阶段，都会受到更严重的认知障碍的影响。

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