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首页> 外文期刊>Journal of Neurology, Neurosurgery and Psychiatry >FP2-3?Ten years of paediatric neuro-oncology surgery: quantifying and predicting complications after surgery for intracranial tumour excision
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FP2-3?Ten years of paediatric neuro-oncology surgery: quantifying and predicting complications after surgery for intracranial tumour excision

机译:FP2-3?十年儿科神经肿瘤手术:对颅内肿瘤切除术后的手术后量化和预测并发症

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To measure complications of paediatric neurooncology surgery using the Clavien Dindo grading scale, and identify predictors of surgical morbidity.Retrospective review of prospectively collected data.All paediatric patients treated with craniotomy for excision of intracranial tumour between 2008 and 2017 in a single tertiary paediatric neurosurgery centre.Demographics, surgical details and perioperative complications were prospectively recorded between 0 and 30 days post operatively. These were retrospectively graded using the CD scale. Data analysis was done in R using logistic regression. Significance was defined as p<0.05Between 3/1/2008 and 21/12/2017 there were 322 operations, on 254 patients (142 Male). Median age at surgery was 9 years (IQR 4–13 years). 48% were without complication on the CD scale. Maximum CD grade complication for each procedure was 1 in 11%, 2 in 19%, 3A in 2%, 3B in 14%, and 4 in 0.6% of operations. 30?day mortality was 0.9%. CD grade of 3B or over was associated with infratentorial tumours (OR 2.24; CI 1.10–4.68; p=0.004) and WHO grade III tumours (OR 4.12; CI 1.56–10.86; p=0.028).Complications in paediatric neurooncology surgery are common overall, but our results are favourable in comparison to the literature. The CD scale has limitations in neurosurgery but gives insight into the health economic impact of complications. Infratentorial tumours, and WHO grade III tumours were associated with increased morbidity.
机译:使用Clavien DINDO分级规模测量小儿神经科学手术的并发症,并鉴定手术发病率的预测因子。对期收集数据的预测因素综述。2008年至2017年颅内肿瘤切断治疗的所有儿科患者在一次三级儿科神经外科中心。emographics,手术细节和围手术期并发症在手术中张贴0到30天之间。这些是使用CD刻度回顾性分级的。使用逻辑回归在R中完成数据分析。意义被定义为P <0.05bberwweh 3/1/2008和21/12/2017在254名患者(142名男性)上有322个操作。手术中位年龄为9年(IQR 4-13岁)。 48%没有对CD刻度的并发症。每种程序的最大CD等级并发症为11%,2%,2%,3B,14%,3%,4%,0.6%的操作。 30?白年死亡率为0.9%。 3b或结束的Cd等级与Infratential肿瘤(或2.24; CI 1.10-4.68; p = 0.004)和WHO级肿瘤(或4.12; CI 1.56-10.86; p = 0.028)。特子神经科学手术中的可符合法性是常见的总体而言,但我们的结果与文献相比是有利的。 CD规模具有神经外科的局限性,但能够深入了解并发症的健康经济影响。 INFRATENTIOL肿瘤,以及III级肿瘤的发病率增加有关。

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