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首页> 外文期刊>Journal of orthopaedic research >Risk factors for radiographic joint space narrowing and patient reported outcomes of post-traumatic osteoarthritis after ACL reconstruction: Data from the MOON cohort
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Risk factors for radiographic joint space narrowing and patient reported outcomes of post-traumatic osteoarthritis after ACL reconstruction: Data from the MOON cohort

机译：射线照相关节空间狭窄和患者危险因素报告了ACL重建后创伤后骨关节炎的结果：来自月球队列的数据

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The Multicenter Orthopaedic Outcomes Network (MOON) is an NIH-funded prospective, longitudinal cohort of over 3,500 patients who have undergone anterior cruciate ligament reconstruction (ACLR) by 14 sports medicine surgeons at 7 academic medical centers. Patient reported outcome questionnaires (PRO's) are completed at baseline and multiple timepoints after surgery, and a nested cohort of patients return for radiographs to assess the development of joint space changes. We review the risk factors for worse patient reported outcomes, the predictors of clinically significant symptoms of post-traumatic osteoarthritis (PTOA), and the factors associated with more radiographic joint space narrowing. Baseline PRO's were highly predictive of follow-up scores. Factors associated with worse PRO's at 2 and 6 years included female sex, higher BMI, smoking, less education, allograft, medial meniscectomy, or repair, and chondral injury. Partial lateral meniscectomy was unexpectedly associated with better PRO's. Factors associated with clinically significant symptoms of PTOA at 2 and 6 years included subsequent surgery, meniscal pathology, and chondral injury. Factors associated with narrower medial compartment joint space width included medial meniscectomy, medial meniscus repair, and increased age. Medial joint space width was slightly wider overall for the ACLR knees compared to the contralateral normal knees. Future studies will evaluate PRO's and radiographs at 10-year follow-up. (c) 2017 Orthopaedic Research Society. Published by Wiley Periodicals, Inc. J Orthop Res 35:1366-1374, 2017.
机译：多中心矫形结果网络（月亮）是NIH资助的前瞻性，纵向群组超过3,500名患者，其在7学术医疗中心的14名体育外科医生接受了14名体育外科医生。患者报告的结果问卷（Pro's）在外科后完成基线和多个时间点，以及嵌套患者返回射线照片以评估联合空间变化的发展。我们审查了更糟糕的患者报告结果的风险因素，临床上创伤后骨关节炎（PTOA）的临床显着症状的预测因子以及与更多放射线接头空间缩小的因素。基线Pro的高度预测跟进分数。与较差的专业人士有关的因素包括2和6岁，包括女性，更高的BMI，吸烟，较少的教育，同种异体移植，中间凌光切除术或维修，以及核心伤害。部分侧向裂缝切除术意外与更好的专业人士意外相关。与临床显着症状有关临床显着症状的因素，包括2和6岁，包括随后的手术，半月板病理和骨质伤害。与较窄的内侧隔室关节空间宽度相关的因素包括内侧吊坠，内侧弯月面修复和增加的年龄。与对侧普通膝盖相比，内侧接合空间宽度对于ACLR膝盖略宽。未来的研究将在10年的随访中评估Pro和Rictraphss。 （c）2017年骨科研究会。由Wiley期刊出版，Inc.J Orthop Res 35：2017年。

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