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首页> 外文期刊>Journal of oral rehabilitation >A randomised clinical trial on the efficacy of 5% fluorocalcium phosphosilicate-containing novel bioactive glass toothpaste
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A randomised clinical trial on the efficacy of 5% fluorocalcium phosphosilicate-containing novel bioactive glass toothpaste

机译:一种随机临床试验,对含5%氟核磷酸硅酸盐的新型生物活性玻璃牙膏的疗效进行疗效

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摘要

Dentine hypersensitivity (DH) is a common and harrowing dental condition. A novel BioMin-F technology that contains 5% fluorocalcium phosphosilicate bioactive glass has been introduced. It forms fluorapatite, which is more stable towards acid erosion. There is a lack of literature with the utility of this toothpaste in treating DH. Therefore, the authors of this randomised clinical trial have aimed to compare and evaluate the efficacy of 5% fluorocalcium phosphosilicate with an 8% arginine and calcium carbonate and placebo toothpaste. A total of 75 patients clinically diagnosed with DH were randomly divided into three groups: Group A, 5% fluorocalcium phosphosilicate; Group B, 8% arginine and calcium carbonate; and Group C, placebo. The DH was evaluated by tactile and evaporative stimuli, and a visual analogue scale (VAS) was used for evaporative stimuli at pre-baseline, baseline (15 days) and post-baseline (1 month). The results showed symptoms of DH were reduced in all three groups. However, Group A showed a better reduction of DH than the other two groups. The toothpaste containing 5% fluorocalcium phosphosilicate was reported to be more efficacious than the other two toothpastes in managing DH. This novel development opens up a unique opportunity in the prevention and management of DH and may also be beneficial in preventing acid erosion of the tooth surface and in the maintenance of oral hygiene by reducing the effects of plaque accumulation and gingival inflammation.
机译:牙本质超敏反应(DH)是一种常见和令人痛苦的牙齿状况。已经引入了一种新的含有5%氟甲酸碳硅酸钙生物活性玻璃的生物素-F技术。它形成氟磷灰石,对酸腐蚀更稳定。这种牙膏在治疗DH的效用中缺乏文学。因此,该随机临床试验的作者旨在比较和评估5%氟核硅酸钙用8%的精氨酸和碳酸钙和安慰剂牙膏的功效。共有75名临床诊断为DH患者被随机分为三组:A组,5%氟甲硅酸钙; B组,8%精氨酸和碳酸钙;和C组,安慰剂。 DH通过触觉和蒸发刺激评价,并且视觉模拟量表(VAS)用于预基线,基线(15天)和后基线(1个月)的蒸发刺激。结果表明,所有三组都会显示DH的症状。然而,A组比其他两组更好地减少了DH。据报道,含有5%氟甲硅酸钙的牙膏比管理DH的其他两个牙膏更有效。这部新颖的发展在预防和管理DH的情况下开辟了一个独特的机会,也可能有利于预防牙齿表面的酸腐蚀以及通过降低斑块累积和牙龈炎的影响来维持口腔卫生。

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