An integrated biomarker and biophysical modeling approach in support of PEGylated human recombinant PH20 hyaluronidase (PEGPH20) combinatorial dosing strategy

Fathallah Anas M.; Nanavati Charvi; Taverna Darin; Bahn Jesse D.; Thompson Curtis B.

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An integrated biomarker and biophysical modeling approach in support of PEGylated human recombinant PH20 hyaluronidase (PEGPH20) combinatorial dosing strategy

机译：基于聚乙二醇化人重组PH20透明质酸酶（PEGPH20）组合给药策略的综合生物标志物和生物物理学建模方法

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来源
《Journal of pharmacokinetics and pharmacodynamics》 |2017年第suppla期|共2页
作者
Fathallah Anas M.; Nanavati Charvi; Taverna Darin; Bahn Jesse D.; Thompson Curtis B.;
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正文语种 eng
中图分类药学;
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1. An integrated biomarker and biophysical modeling approach in support of PEGylated human recombinant PH20 hyaluronidase (PEGPH20) combinatorial dosing strategy [J] . Fathallah Anas M., Nanavati Charvi, Taverna Darin, Journal of pharmacokinetics and pharmacodynamics . 2017,第Suppla期

机译：基于聚乙二醇化人重组PH20透明质酸酶（PEGPH20）组合给药策略的综合生物标志物和生物物理学建模方法
2. Targeting the Tumor Stroma: the Biology and Clinical Development of Pegylated Recombinant Human Hyaluronidase (PEGPH20) [J] . Wong Kit Man, Horton Kathryn J., Coveler Andrew L., Current oncology reports. . 2017,第7期

机译：靶向肿瘤基质：聚乙二醇化重组人透明质酸酶（PEGPH20）的生物学和临床开发
3. Phase 1 trials of PEGylated recombinant human hyaluronidase PH20 in patients with advanced solid tumours [J] . Jeffrey R Infante, Ronald L Korn, Lee S Rosen, British Journal of Cancer . 2018,第2期

机译：聚乙二醇化重组人透明质酸酶PH20在晚期实体瘤患者中的1期试验
4. Clinical Trial of Recombinant Human PH20 Hyaluronidase's Effect on Subcutaneous Absorption and Pharmacokinetics of a Large Protein Molecule Therapeutic [C] . Richard C. Yocum, Daniel E. Vaughn, Deborah J. Mongiovi, Controlled Release Society Annual Meeting and Exposition . 2007

机译：重组人PH20透明质酸酶对大蛋白分子皮下吸收和药代动力学的影响的临床试验
5. A Systems Approach to Analyze Household Vulnerability to Food Insecurity in Rural Southern Mali Using a Spatially-Explicit Integrated Social and Biophysical Model [D] . Paudel, Rajiv. 2020

机译：利用空间 - 明确的综合社会和生物物理模型分析农村南部粮食不安全性粮食不安全性的系统方法
6. P-288Global Phase 3 Randomized Double-Blind Placebo-Controlled Multicenter Study to Compare Efficacy and Safety of PEGylated Recombinant Human Hyaluronidase (PEGPH20) Plus nab-Paclitaxel and Gemcitabine vs. Placebo Plus nab-Paclitaxel and Gemcitabine [O] . Tempero Margaret, Hingorani Sunil, Zheng Lei, -1

机译：P-288全球3期随机双盲安慰剂对照的多中心研究比较PEG化重组人透明质酸酶（PEGPH20）加nab-紫杉醇和吉西他滨与安慰剂加nab-紫杉醇和吉西他滨的疗效和安全性
7. Pegylated Recombinant Human Hyaluronidase PH20 [O] . 2020

机译：PEG化重组人透明质酸酶pH20

An integrated biomarker and biophysical modeling approach in support of PEGylated human recombinant PH20 hyaluronidase (PEGPH20) combinatorial dosing strategy

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