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首页> 外文期刊>American journal of dentistry >Comparative efficacy of two treatment regimens combining in-office and at-home programs for dentin hypersensitivity relief: A 24-week clinical study
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Comparative efficacy of two treatment regimens combining in-office and at-home programs for dentin hypersensitivity relief: A 24-week clinical study

机译：结合办公室和在家使用的两种治疗方案对牙本质过敏缓解的比较疗效：一项为期24周的临床研究

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Purpose: Dentin hypersensitivity is a significant clinical problem that affects numerous individuals. This sharp pain, arising from exposed dentin in response to external stimuli, can be a particularly uncomfortable and unpleasant sensation for patients, because it interferes with their quality of life. The objective of this 24-week, singlecenter, parallel group, double-blind, stratified and randomized clinical study was to evaluate the clinical efficacy of a single professional treatment with an in-office desensitizing paste followed by twice daily brushing with a desensitizing toothpaste and toothbrush for 24 weeks. Methods: 100 adults with confirmed dentin hypersensitivity were randomly assigned into two groups. One group received a single in-office treatment with a desensitizing paste containing 8% arginine and calcium carbonate (marketed as Colgate Sensitive Pro-Relief Desensitizing Paste and Elmex Sensitive Professional desensitizing paste), after dental scaling, followed by 24 weeks of brushing twice daily with a desensitizing toothpaste containing 8% arginine, calcium carbonate with 1450 ppm fluoride as MFP (marketed as Colgate Sensitive Pro-Relief toothpaste and Elmex Sensitive Professional toothpaste) and using the Colgate Sensitive Pro-Relief toothbrush (Test Group). The other group received a single in-office treatment with Nupro-M pumice prophylaxis paste, after dental scaling, followed by 24 weeks of brushing twice daily with a non-desensitizing toothpaste containing 1450 ppm fluoride as MFP and with the Oral-B Indicator toothbrush (Negative Control Group). Hypersensitivity was reexamined immediately after in-office product application and after 8 and 24 weeks of twice daily brushing. Results: Immediately after professional product application, and after 8 and 24 weeks, subjects assigned to the Test Group demonstrated statistically significant improvements in dentin hypersensitivity compared to subjects assigned to the Negative Control Group in tactile (49.8%, 57.5% and 32.9%, respectively) and air blast (26.0%, 38.4% and 34.3%, respectively) sensitivity scores. The instant reductions in dentin hypersensitivity provided by the single professional application of a desensitizing paste for in-office use, containing 8% arginine and calcium carbonate were maintained by twice daily brushing with the 8% arginine, calcium carbonate toothpaste with 1450 ppm fluoride as MFP and the Colgate Sensitive Pro-Relief toothbrush for at least 24 weeks.
机译：目的：牙本质过敏是影响许多个体的重大临床问题。由于暴露的牙本质响应外部刺激而引起的这种剧烈疼痛，可能会干扰患者的生活质量，给患者带来特别不舒服和不愉快的感觉。这项为期24周，单中心，平行组，双盲，分层和随机临床研究的目的是评估在办公室使用脱敏膏，然后每天两次使用脱敏牙膏和脱敏牙膏进行单一专业治疗的临床疗效。牙刷24周。方法：将确诊为牙本质过敏的100名成人随机分为两组。一组在牙科洗牙后，用含有8％精氨酸和碳酸钙的脱敏膏进行单次办公室治疗（以高露洁敏感型Pro-Relief脱敏膏和Elmex Sensitive Professional脱敏膏销售），然后每天进行24周刷牙两次使用含有8％精氨酸的脱敏牙膏，碳酸钙和1450 ppm氟化物作为MFP（以高露洁敏感专业缓解型牙膏和Elmex敏感专业洁齿产品销售），并使用高露洁敏感专业缓解型牙刷（测试组）。另一组在牙科洗牙后使用Nupro-M浮石预防性糊剂在办公室进行单次治疗，然后每天24周用含1450 ppm氟化物作为MFP的非脱敏牙膏和Oral-B指示剂牙刷刷牙两次。 （阴性对照组）。在办公室使用产品后以及每天两次刷牙的8和24周后立即重新检查过敏反应。结果：在专业产品应用后，8周和24周后，分配给测试组的受试者与触觉分配给阴性对照组的受试者相比，显示出牙本质过敏的统计学显着改善（分别为49.8％，57.5％和32.9％） ）和鼓风（分别为26.0％，38.4％和34.3％）敏感性得分。通过每天两次刷牙8％精氨酸碳酸钙牙膏和1450 ppm氟化物作为MFP，可以保持一次专业使用的脱敏糊剂（包含8％的精氨酸和碳酸钙）的一次性使用，从而立即降低牙本质过敏。和高露洁（Colgate）敏感型Pro-Relief牙刷至少持续24周。

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