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首页> 外文期刊>American journal of dentistry >Dentin hypersensitivity reduction of a new toothpaste containing 8.0% arginine and 1450 ppm fluoride: An 8-week clinical study on Chinese adults
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Dentin hypersensitivity reduction of a new toothpaste containing 8.0% arginine and 1450 ppm fluoride: An 8-week clinical study on Chinese adults

机译：减少含有8.0％精氨酸和1450 ppm氟化物的新型牙膏的牙本质过敏症：针对中国成年人的8周临床研究

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Purpose: To present the results of an 8-week dentin hypersensitivity clinical study in which the efficacy of a new Pro-Argin~(TM)formula toothpaste, with gentle whitening benefits, containing 8.0% arginine, a high cleaning calcium carbonate system, and 1450 ppm fluoride as sodium monofluorophosphate (MFP) was compared to that of a commercial Pro-Argin formula toothpaste containing 8.0% arginine, calcium carbonate, and 1450 ppm fluoride as MFP and a negative control toothpaste containing calcium carbonate and 1450 ppm fluoride as MFP. Methods: An 8-week clinical study, with 121 subjects, was conducted in Chengdu, Sichuan, China, using a double-blind, stratified, three-treatment design. Tactile and air blast sensitivity assessments were used to compare the efficacy of the three products. Results: This clinical study demonstrated that the new Pro-Argin formula toothpaste provided a significant reduction in dentin hypersensitivity when used over a period of 8 weeks. The study also showed that the new toothpaste provided significantly greater reductions (P< 0.05) in dentin hypersensitivity in response to tactile (64.4%, 71.1%, and 61.0%) and air blast (40.7%, 58.8%, and 74.4%) stimuli than the negative control toothpaste containing 1450 ppm fluoride after 2, 4, and 8 weeks of product use, respectively. The results for the new toothpaste did not differ significantly from those of the positive control toothpaste at all time points in the study.
机译：目的：介绍一项为期8周的牙本质过敏临床研究的结果，其中一种新型的Pro-Argin〜（TM）配方牙膏具有8.0％的精氨酸，高清洁度的碳酸钙系统和温和的美白功效，并且具有良好的美白效果。将1450 ppm氟化物单氟磷酸钠（MFP）与含有8.0％精氨酸，碳酸钙和1450 ppm氟化物作为MFP的商用Pro-Argin配方牙膏以及含有碳酸钙和1450 ppm氟化物的阴性对照牙膏进行了比较。方法：采用双盲，分层，三治疗设计，在中国四川成都进行了为期8周的临床研究，共121位受试者。触觉和鼓风敏感性评估用于比较这三种产品的功效。结果：这项临床研究表明，新Pro-Argin配方牙膏使用8周后，可显着降低牙本质过敏。研究还表明，新的牙膏对触觉（64.4％，71.1％和61.0％）和鼓风（40.7％，58.8％和74.4％）刺激的反应使牙本质超敏性明显降低（P <0.05）。在产品使用后第2、4和8周分别比含1450 ppm氟化物的阴性对照牙膏要多。在研究的所有时间点，新牙膏的结果与阳性对照牙膏的结果均无显着差异。

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