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首页> 外文期刊>Journal of stroke and cerebrovascular diseases: The official journal of National Stroke Association >Fish Consumption and Stroke Risk: A Meta-Analysis of Prospective Cohort Studies
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Fish Consumption and Stroke Risk: A Meta-Analysis of Prospective Cohort Studies

机译：鱼类消费和行程风险：预期队列研究的荟萃分析

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Background: Inconsistent results of the association between fish consumption and stroke risk have been indicated in previous epidemiological studies. Therefore, we performed a meta-analysis of prospective cohort studies to estimate the impact of fish consumption on stroke risk. Methods: The PubMed and EMBASE databases were searched through a computer search. Prospective cohort studies satisfying predetermined inclusion criterion were included. Random-effect model was adopted in this meta-analysis. Analysis of subgroup, sensitivity, publication bias, dose-response, power, and quality of evidence was also conducted. Results: Thirty one publications including 33 independent prospective cohort studies were identified in this meta-analysis. In the primary analysis of the highest versus lowest categories of fish consumption, pooled results indicated that a significant trend toward an inverse association between fish intake and stroke risk (HR = .90, 95% confidence interval [CU .85-.96). Further subgroup analyses indicated an inverse association was more pronounced in the group of hemorrhagic stroke (HR=.88, 95% CI .80-.96), female (HR =.83, 95% CI .75-.92), and Asia-Pacific (HR = .87, 95% CI .80-.95). Both the funnel plot and Egger tests suggested no evidence of publication bias. Dose-response analysis showed a linear relationship between fish intake and stroke and the risk of stroke decreased by 2%-12% with increasing intake of fish up to 100-700 g/week. According to the NutriGrade scoring system, the level of metaevidence quality was moderate. Conclusions: Based on current evidence from prospective cohort studies, we concluded that fish consumption was associated with a decreased risk of stroke.
机译：背景：在以前的流行病学研究中表明了鱼类消费和卒中风险之间的关联的不一致结果。因此，我们对前瞻性队列研究进行了荟萃分析，以估计鱼类消费对卒中风险的影响。方法：通过计算机搜索搜索PubMed和Embase数据库。包括令人满意的综合标准的预期队列研究。在该荟萃分析中采用随机效应模型。还进行了分析亚组，敏感性，出版物偏见，剂量反应，力量和证据质量。结果：在该荟萃分析中确定了33项独立预期队列研究，包括33项独立预期队列研究。在对最高类别的鱼类消费的主要分析中，合并结果表明，鱼摄入和中风风险之间的反比关联的显着趋势（HR = .90,95％置信区间[Cu .85-.96）。进一步的亚组分析表明，出血性卒中组（HR = .88,95％CI.80-.96），女性（HR = .83,95％CI .75-.92）中，副关联更加明显。和亚太地区（HR = .87,95％CI .80-.95）。漏斗情节和egger测试都没有提出出版物偏见的证据。剂量 - 反应分析显示鱼摄入和中风之间的线性关系，中风的风险降低2％-12％，随着鱼的摄入量增加到100-700克/周。根据营养得分系统，荟萃质量的水平适度。结论：基于来自前瞻性队列研究的现有证据，我们得出结论，鱼类消费与下降风险降低有关。

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