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首页> 外文期刊>Journal of stroke and cerebrovascular diseases: The official journal of National Stroke Association >Low Body Mass Index is a Poor Prognosis Factor in Cardioembolic Stroke Patients with NonValvular Atrial Fibrillation
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Low Body Mass Index is a Poor Prognosis Factor in Cardioembolic Stroke Patients with NonValvular Atrial Fibrillation

机译：低体重指数是患有非血管性心房颤动的心脏栓塞患者的预后差因素差

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BackgroundThe relationship between body mass index (BMI) and the severity of cardioembolic stroke (CES) remains poorly understood. MethodA total of 419 consecutive CES patients with nonvalvular atrial fibrillation (NVAF), and with a modified Rankin Scale (mRS) score of 0 or 1 before onset admitted within 48hours after onset to the Hirosaki Stroke and Rehabilitation Center were studied. The patients were divided into three groups, low BMI (L-BMI;n?=?36, BMI < 18.5 kg/m2), normal BMI (N-BMI;n?=?284, 18.5 ≤ BMI < 25.0), and high BMI (H-BMI;n?=?99, BMI ≥ 25.0). We compared stroke severity and functional outcome among the three groups. ResultsStroke severity on admission, assessed by the National Institutes of Health Stroke Scale (NIHSS) showed that patients with L-BMI had the highest NIHSS score (median, 16 [11-25]), followed by N-BMI and H-BMI (11 [5-19] and 9 [3-19],P?=?.002). Functional outcome at discharge, assessed by mRS, was most severe in L-BMI patients (5 [3-5]), followed by N-BMI and H-BMI (3 [1-4] and 2 [1-4],P?=?.001). Multivariate analyses revealed that L-BMI was a significant determinant of severe stroke (NIHSS scores ≥8) at admission (odds ratio [OR] to N-BMI?=?2.79, 95% confidence interval [CI], 1.17-7.78,P?=?.02) and poor functional outcome (mRS scores ≥3) at discharge (OR?=?2.53, 95% CI, 1.12-6.31,P?=?.02). However, H-BMI did not affect stroke severity at admission or functional outcome at discharge. ConclusionLow BMI is a risk factor for severe stroke on admission and unfavorable functional outcome at discharge in Japanese CES patients with NVAF.
机译：背景技术体重指数（BMI）与心脏栓塞中风（CES）的严重程度之间的关系仍然难以理解。方法总共419例连续的CES患者，具有非衰弱性心房颤动（NVAF），并且在发病后在48小时内入院前的改良Rankin Scale（MRS）得分为0或1，研究过Hirosaki中风和康复中心。将患者分为三组，低BMI（L-BMI; N？36，BMI <18.5 kg / m 2），正常BMI（N-BMI; N？=Δ284,18.5≤bmi<25.0），和高BMI（H-BMI; N？=α= 99，BMI≥25.0）。我们比较了三组中的中风严重程度和功能结果。 Crycepterstrous游程度在入学时，由国家卫生卒中量表（NIHSS）评估显示，L-BMI患者具有最高的NIHSS评分（中位数，16 [11-25]），其次是N-BMI和H-BMI（ 11 [5-19]和9 [3-19]，p？= 002）。通过MRS评估的放电的功能结果在L-BMI患者中最严重（5 [3-5]），其次是N-BMI和H-BMI（3 [1-4]和2 [1-4]， p？= 001）。多变量分析表明，L-BMI在入院时是严重中风（NIHSS评分≥8）的重要决定因素（差距为N-BMI [或] =？2.79,95％置信区间[CI]，1.17-7.78，P ？=Δ.02）和在放电时差的功能结果（SICARE≥3）（或？=？2.53,95％CI，1.12-6.31，P？= 02）。然而，H-BMI在放电时不影响入院或功能结果时的中风严重程度。结论Llow BMI是日本CES NVAF患者的入院和不利功能结果的严重卒中的危险因素。

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