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首页> 外文期刊>Journal of stroke and cerebrovascular diseases: The official journal of National Stroke Association >Incidence and Predictors of the In-stent Restenosis after Vertebral Artery Ostium Stenting
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Incidence and Predictors of the In-stent Restenosis after Vertebral Artery Ostium Stenting

机译：椎动脉矫形术后支架再狭窄的发病率和预测

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BackgroundThe incidence and predictors for in-stent restenosis (ISR) was not fully explored. We aim to investigate the incidence and predictors of ISR after stenting at the origin of vertebral artery. Materials and MethodsTwo hundred and six patients with 229 stents implantation between July 1, 2005 and July 31, 2015 were included in the study. All patients underwent conventional clinical and angiographic (digital subtraction angiography) follow-up at around 6 months post procedure. ISR was defined as greater than 50% stenosis within or immediately (within 5 mm) adjacent to the stent. Multivariate Cox regression analyses were utilized to investigate the predictors for ISR. ResultsThe ISR was found in 30 patients (30/206, 14.6%) with 31 lesions (31/229, 13.5%) with the mean follow-up duration of 11.1-month (range: 3 - 92 months). Stent diameter (hazard ratio 0.504, 95% confidence interval 0.294 - 0.864) was an independent predictor for ISR. ConclusionISR rate after Vertebral artery ostium stent placement is acceptable, which was conversely associated with the stent diameter.
机译：背景技术没有充分探索支架再狭窄（ISR）的发病率和预测因子。我们的目标是探讨椎间动脉起源后ISR的发病率和预测因子。 2005年7月1日至2015年7月1日至7月31日之间的229个支架植入患者的材料和方法被纳入该研究。所有患者均接受常规临床和血管造影（数字减法血管造影）在术后6个月内随访。 ISR被定义为靠近支架内或紧邻（5 mm内）的大于50％的狭窄。利用多变量COX回归分析来研究ISR的预测因子。结果患者在30名患者（30/206,14.6％）中发现，具有31个病变（31/229,13.5％），平均随访期为11.1个月（范围：3-92个月）。支架直径（危险比0.504,95％置信区间0.294 - 0.864）是ISR的独立预测因子。结论椎动脉ostium支架放置术后的速率是可接受的，这与支架直径相反。

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