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首页> 外文期刊>Journal of stroke and cerebrovascular diseases: The official journal of National Stroke Association >Arterial Stiffness in Subacute Stroke: Changing Pattern and Relationship with Functional Recovery
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Arterial Stiffness in Subacute Stroke: Changing Pattern and Relationship with Functional Recovery

机译：亚急性中风中的动脉僵硬：改变功能恢复的模式和关系

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Background: To examine changing patterns in arterial stiffness and functional outcome in patients with subacute stroke, and to determine which parameter shows a strong correlation with the reversal of arterial stiffness, during a 3-month period of comprehensive rehabilitation therapy. Methods: This descriptive, observational cohort study enrolled 60 patients (43 male and 17 female; average age, 62.7 years), and all received conventional rehabilitation therapy, during a 3-month period. Brachialankle pulse wave velocity (baPWV) was measured as an index of arterial stiffness. Functional assessments included the 6-minute walk test (6MWT), Fugl-Meyer Assessment of hemiparetic upper and lower limbs, the functional ambulatory category, the Berg balance scale, the Korean Mini-Mental Status Examination, and the Korean-Modified Barthel Index. All measurements were conducted at baseline and 1 and 3 months after stroke onset. Results: Rehabilitation therapy resulted in a statistically significant improvement in baPWV since 3 months post stroke. Another functional outcome measure showed statistically significant improvements since 1 month after rehabilitation. Multivariable linear regression analysis revealed that a change in baPWV was significantly correlated with changes in the 6MWT. Conclusions: Three months of comprehensive rehabilitation therapy led to statistically significant improvements in arterial stiffness and functional outcomes during the subacute phase of stroke. Thus, the comprehensive rehabilitation focused on improving gait endurance would be warranted in subacute stroke patients.
机译：背景：检查亚急性中风患者的动脉僵硬和功能结果中的改变模式，并确定哪个参数与动脉僵硬度的逆转相关，在综合康复治疗的3个月期间。方法：这种描述性，观察队队列研究注册了60名患者（43名男性和17名女性;平均年龄，62.7岁），并在3个月期间接受常规康复治疗。肱脉冲波速度（BAPWV）被测量为动脉刚度指数。功能评估包括6分钟的步行试验（6MWT），Fugl-Meyer对偏瘫和下肢的评估，功能性的动态类别，Berg平衡规模，韩国迷你精神状态考试和韩国改进的条形指数。所有测量均在基线和卒中发作后1和3个月进行。结果：康复疗法由于行程后3个月以来，BapWV导致统计学上显着改善。自康复后1个月以来，另一种功能结果措施显示出统计学上的改善。多变量线性回归分析显示，BAPWV的变化与6MWT的变化显着相关。结论：三个月的综合康复治疗导致卒中亚急性期动脉僵硬和功能性结果的统计学意义。因此，在亚急性中风患者中有必要有重点康复，重点是改善步态耐力。

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