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首页> 外文期刊>Journal of stroke and cerebrovascular diseases: The official journal of National Stroke Association >Clinical Course and Outcomes of Small Supratentorial Intracerebral Hematomas
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Clinical Course and Outcomes of Small Supratentorial Intracerebral Hematomas

机译：小超前脑血肿的临床课程和结果

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Background and Purpose: Intracerebral hemorrhage (ICH) volume, particularly if >= 30 mL, is a major determinant of poor outcome. We used a multinational ICH data registry to study the characteristics, course, and outcomes of supratentorial hematomas with volumes <30 mL. Methods: Basic characteristics, clinical and radiological course, and 30-day outcomes of these patients were recorded. Outcomes were categorized as early neurological deterioration (END), hematoma expansion, Glasgow Outcome Scale (GOS), and in-hospital death. Poor outcome was defined as composite of in-hospital death and severe disability (GOS = 3). Comparison was conducted based on hemorrhage location. Logistic regression using dichotomized outcome scales was applied to determine predictors of poor outcome. Results: Among 375 cases of supratentorial ICH with volumes <30 mL, expansion and END rates were 19.2% and 7.5%, respectively. Hemorrhage growth was independently associated with END (odds ratio: 28.7, 95% confidence interval [CI]: 8.51-96.5; P < .0001). Expansion rates did not differ according to ICH location. Overall, 13.9% (exact binomial 95% CI: 10.5-17.8) died in the hospital and 29.1% (CI: 24.5-34.0) had severe disability at 30 days; there was a cumulative poor outcome rate of 42.9% (CI: 37.9-48.1). Age, admission Glasgow Coma Scale, intraventricular extension, and END were independently associated with poor outcome. There was no difference in poor outcome rates between lobar and deep locations (40.2% versus 43.8%, P = .56). Conclusion: Patients with supratentorial ICH <30 mL have high rates of poor outcome at 30 days, regardless of location. Nearly 1 in 5 hematomas <30 mL expands, leading to END or death. (C) 2017 National Stroke Association. Published by Elsevier Inc. All rights reserved.
机译：背景和目的：脑出血（ICH）体积，特别是如果> = 30毫升，是结果差的主要决定因素。我们使用跨国公司数据登记处研究了血管血肿的特征，课程和结果，其中包含<30毫升。方法：记录基本特征，临床和放射性课程，并记录了这些患者的30天后。结果被分类为早期神经劣化（终端），血肿扩张，格拉斯哥结果规模（GOS）和医院死亡。结果不佳被定义为入院死亡和严重残疾的综合（GOS = 3）。基于出血位置进行比较。应用了使用二分化结果尺度的逻辑回归来确定差的结果的预测因子。结果：375例超前素案例，累积<30毫升，膨胀和汇率分别为19.2％和7.5％。出血生长与末端独立相关（差距：28.7,95％置信区间[CI]：8.51-96.5; P <.0001）。根据ICH位置，扩展率没有差异。总体而言，13.9％（精确二项式95％CI：10.5-17.8）在医院死亡，29.1％（CI：24.5-34.0）在30天内患有严重的残疾;累计差的成果率为42.9％（CI：37.9-48.1）。年龄，入学格拉斯哥昏迷尺度，脑室延伸和末端与差的结果无关。洛巴尔和深层位置之间的结果差异不差异（40.2％，与43.8％，p = .56）。结论：患有Supratential ICH <30 mL的患者在30天内患者高差，无论位置如何。近1次血液血肿<30毫升扩展，导致结束或死亡。 （c）2017国家冲程协会。由elsevier Inc.保留所有权利发布。

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