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首页> 外文期刊>Journal of stroke and cerebrovascular diseases: The official journal of National Stroke Association >Differentiating Stroke and Seizure in Acute Setting-Perfusion Computed Tomography?
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Differentiating Stroke and Seizure in Acute Setting-Perfusion Computed Tomography?

机译：在急性设定灌注计算断层扫描中的区分中风和癫痫发作？

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Background: Perfusion computed tomography (PCT) is part of acute stroke protocol in many hospitals; however, its clinical utility is still being disputed. Beyond its use in core and penumbra estimation, there is also a question about PCT role in stroke mimics diagnosis. Case series or small, retrospective studies showed equivocal results. This is the first published prospective, comparative study on PCT in differentiating stroke and seizure in acute setting. Methods: Patients with acute focal neurologic deficits and without acute ischemic lesions on routine CT underwent PCT and electroencephalography (EEG) within 12 hours after symptom onset. Perfusion parameters were set up as asymmetry indices for corresponding regions of brain hemispheres. EEG findings were assigned to 1 of 5 classes. Neurologic examination was performed using the National Institutes of Health Stroke Scale (NIHSS). Follow-up noncontrast computed tomography was performed on the third day after symptom onset. If no CT changes appeared, magnetic resonance diffusion-weighted imaging was conducted. Results: Final diagnosis was hemispheric ischemic stroke in 17 patients and focal neurologic deficits in the course of seizures (post-and intraictally) in 12 patients. Those groups were significantly different only in one single PCT parameter-time to peak (TTP)-in the lateral part of the middle cerebral artery territory. Analyzed groups were not significantly different in the NIHSS scores and the EEG evaluation. Conclusions: TTP may stay relatively when seizure is a cause of focal neurologic deficits, but not stroke. Further, large, prospective studies are necessary to verify the results. Key Words: Perfusion computed tomography-seizures-Todd's paresis-status epilepticus-stroke.
机译：背景：灌注计算机断层扫描（PCT）是许多医院中急性笔划协定的一部分;然而，其临床效用仍在争议。除了在核心和半影估计中的使用之外，还存在关于中风模仿诊断的PCT作用的问题。案例系列或小型，回顾性研究表明了果断的结果。这是第一次出版的术语前瞻性，对急性设定中卒中和癫痫发作的PCT的比较研究。方法：急性局灶性神经系统缺陷患者，无急性缺血性病变在常规CT症状后12小时内接受PCT和脑电图（EEG）。将灌注参数设置为脑半球相应区域的不对称指标。 EEG调查结果分配给5个课程中的1个。使用国家卫生卒中量表（NIHSS）进行神经系统检查。随访非共移计算机断层扫描是在症状发作后第三天进行的。如果没有出现CT变化，则进行磁共振扩散加权成像。结果：最终诊断为17例患者的半球缺血性脑卒中，在12名患者中癫痫发作过程中的局灶性神经系统缺陷。这些基团仅在一个单一PCT参数 - 峰值（TTP） - 在中间脑动脉区域的侧部中有显着差异。分析的群体在NIHSS分数和EEG评估中没有显着差异。结论：当癫痫发作是局灶性神经系统缺陷的原因，但TTP可能保持相对较小。此外，需要大，前瞻性研究才能验证结果。关键词：灌注计算断层扫描 - 癫痫发作-TODD的谱系状态癫痫卒中。

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