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首页> 外文期刊>Journal of stroke and cerebrovascular diseases: The official journal of National Stroke Association >Recurrent Stroke, Myocardial Infarction, and Major Vascular Events during the First Year after Acute Ischemic Stroke: The Multicenter Prospective Observational Study about Recurrence and Its Determinants after Acute Ischemic Stroke I
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Recurrent Stroke, Myocardial Infarction, and Major Vascular Events during the First Year after Acute Ischemic Stroke: The Multicenter Prospective Observational Study about Recurrence and Its Determinants after Acute Ischemic Stroke I

机译：急性缺血性脑卒中后的第一年复发性中风，心肌梗死和主要血管事件：急性缺血性中风后复发及其决定因素的多中心前瞻性观察研究

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Background: Patients with acute ischemic stroke (AIS) are at high risk of subsequent vascular events. The aim of this study was to estimate rates of recurrent stroke, myocardial infarction (MI), and major vascular events during the first year after AIS in Korea. Methods: Through a multicenter stroke registry in Korea, 12,227 consecutive cases of AIS were identified between November 2010 and May 2013 and were followed up for recurrent stroke, MI, and major vascular events up to 1 year after stroke. Results: Cumulative 30-day, 90-day and 1-year rates were 2.7%, 3.9%, and 5.7% for recurrent stroke; .1%, .3%, and .5% for MI; and 8.1%, 10.6%, and 13.7% for major vascular events, indicating that the early period is at high risk of recurrent stroke and major vascular events. The risk of recurrent stroke was substantially higher than the risk of MI: 13.0 times at 90 days and 11.4 times at 1 year. Compared to those with small-vessel occlusion (SVO), those with ischemic stroke subtypes other than SVO had a higher risk of recurrent stroke as well as major vascular events. Other common independent predictors for recurrent stroke and major vascular events were diabetes and prior stroke history. Conclusions: During the first year after AIS, one in 18 had recurrent stroke and one in 7 major vascular events. More than two thirds of recurrent stroke and three quarters of major vascular events developed within 90 days in a Korean cohort of stroke patients. Better prevention strategies are required for high-risk patients during this high-risk period.
机译：背景：急性缺血性卒中（AIS）的患者处于血管事件的高风险。本研究的目的是估计韩国AIS后第一年的复发性中风，心肌梗塞（MI）和主要血管事件的率。方法：通过韩国的多中心行程登记，2010年11月至2013年5月在2013年11月期间识别了12,227案，并随访了卒中后1年的复发性中风，MI和主要血管事件。结果：累积30天，90天和1年的率为2.7％，3.9％和5.7％，适用于复发行程; MI，0.3％，.3％，.5％;主要血管事件的8.1％，10.6％和13.7％，表明早期期具有复发性卒中和主要血管事件的高风险。复发中风的风险基本上高于MI的风险：13.0次在90天，1年的11.4倍。与小血管闭塞（SVO）的那些相比，除了SVO之外的缺血性卒中亚型的那些具有更高的复发性卒中风险以及主要的血管事件。其他常见的独立预测因子用于复发性卒中和主要血管事件是糖尿病和先前的卒中史。结论：在AIS后的第一年，18人中有一个复发性中风，其中一个主要的血管事件。在韩国队列患者的韩国队列90天内，超过三分之二的复发中风和四分之三的主要血管事件。在这种高风险期间，高风险患者需要更好的预防策略。

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