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首页> 外文期刊>Journal of stroke and cerebrovascular diseases: The official journal of National Stroke Association >Gastrointestinal Bowel Obstruction in Acute Ischemic Stroke: Incidence, Risk Factors, and Outcomes in a U.S. Nationwide Analysis of 3,998,667 Hospitalizations
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Gastrointestinal Bowel Obstruction in Acute Ischemic Stroke: Incidence, Risk Factors, and Outcomes in a U.S. Nationwide Analysis of 3,998,667 Hospitalizations

机译：急性缺血性中风中的胃肠肠梗阻：美国的发病率，危险因素和结果。全国范围内的3,998,667家住院治疗

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Objective The prognosis from acute ischemic stroke (AIS) is worsened by poststroke medical complications. The incidence, risk factors, and outcomes of gastrointestinal bowel obstruction (GIBO) in AIS are not known. Methods We queried the Nationwide Inpatient Sample (2002-2011) to identify all patients with a primary diagnosis of AIS and subsets with and without a secondary diagnosis of GIBO without hernia. Multivariable analysis was utilized to identify risk factors for GIBO in AIS patients and the association between GIBO, in-hospital complications, and outcomes. Results We identified 16,987 patients with GIBO (.43%) among 3,988,667 AIS hospitalizations and 4.2% of these patients underwent surgery. In multivariable analysis, patients with 75+?years of age were two times as likely to suffer GIBO compared to younger patients ( P ??.0001). African Americans were 42% more likely to have GIBO compared to Whites ( P ??.0001). Stroke patients with pre-existing comorbidities (coagulopathy, cancer, blood loss anemia, and fluid/electrolyte disorder) were more likely to experience GIBO (all P ??.0001). AIS patients with GIBO were 184% and 39% times more likely to face moderate-to-severe disability and in-hospital death, respectively ( P ??.0001). GIBO occurrence increased length of stay and total costs by an average of 9.7 days and $22,342 ( P ??.0001). Conclusion GIBO is a rare but burdensome complication of AIS, associated with complications, disability, and mortality. The risk factors identified in this study aim to encourage the monitoring of patients at highest risk for GIBO. The predominant form of stroke-related GIBO is nonmechanical obstruction, although the causative relationship remains unknown. ]]>
机译：目的是急性缺血性卒中（AIS）的预后通过失败的医疗并发症恶化。 AIS中胃肠肠梗阻（GIBO）的发病率，危险因素和结果是尚不清楚的。方法我们询问全国性住院样本（2002-2011），以识别所有患者初步诊断AIS和亚群，没有疝气的二次诊断。利用多变量分析来鉴定AIS患者的GIBO的危险因素，以及吉布，医院内并发症和结果之间的关联。结果我们鉴定了16,987名吉布（.43％）的患者，3,988,667 AIS住院，4.2％的这些患者接受了手术。在多变量分析中，与较年轻的患者相比，患有75岁以上的患者的患者患有痛苦的可能性，而患有痛苦的可能性（P？＆ 0001）。与白人相比，非洲裔美国人可能会有42％的可能性，而吉佛（P？＆ 0001）。患有预先存在的合并症（凝血病，癌症，血液丧失贫血和液体/电解质病症）的中风患者更可能经历GIBO（所有p？0001）。 AIS患有Gibo患者分别面临中度至严重残疾和医院死亡的可能性患者184％和39％倍增（P？＆ 0001）。 Gibo发生的寿命长度和总成本的平均成本平均为9.7天和22,342美元（P？＆ 0001）。结论GIBO是一种罕见但繁重的AIS，与并发症，残疾和死亡率相关。本研究中确定的危险因素旨在鼓励在吉布的最高风险监测患者。脑卒中相关的Gibo的主要形式是非机械阻塞，尽管致病关系仍然未知。 ]]>

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