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首页> 外文期刊>Journal of stroke and cerebrovascular diseases: The official journal of National Stroke Association >Thrombolysis Alert in Hassan II University Teaching Hospital of Fez (Morocco): A Prospective Study of 2 Years
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Thrombolysis Alert in Hassan II University Teaching Hospital of Fez (Morocco): A Prospective Study of 2 Years

机译：哈桑二世大学教学院（摩洛哥）溶栓栓塞警报：2年的前瞻性研究

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Background: Thrombolysis alert (TA) is a procedure triggered every time a patient consults for sudden focal neurological deficit within 4.5 hours. Objective: We aimed to determine firstly the etiological profile of TA and secondly to evaluate the delays in the management not only of thrombolyzed patients but also of nonthrombolyzed patients to determine the intrahospital delays to optimize. Methods: Patients aged over 18 years who consulted for sudden focal neurological deficit within 4.5 hours for whom a TA has been triggered were included. Patients admitted within 4.5 hours for which a TA has not been triggered were not included. Patients with sudden focal neurological deficit who consulted more than 4.5 hours, but for whom TA has been triggered, were also included. Results: We included 313 patients. The average onset-to-door time was 125.59 +/- 62.78 minutes with an average National Institutes of Health Stroke Scale scores of 11.29 +/- 5.98. The average door-toimaging time was 28.36 +/- 20.62 minutes. Ischemic stroke (IS) was the most common cause (70.3%), followed by hemorrhagic stroke (11.8%). Other nonstroke causes (stroke mimics) represented 17.9% of cases. They were seizures (46.4%), conversion disorders (26.8%), hypoglycemia (10.7%), brain tumors (10.7%), chronic subdural hematoma (1.8%), carbon monoxide intoxication (1.8%), and cavernoma (1.8%). Forty-six patients had been thrombolyzed. The average door-to-needle time was 90.89 +/- 34.48 minutes. After 3 months, 52.1% of thrombolyzed patients were autonomous (modified Rankin scale between 0 and 2). Two patients had died (4.3%), all in the first week after the IS. Conclusion: Our study shows that efforts need to be made at the extra-hospital and intra-hospital level to improve delays to increase the proportion of the thrombolyzed patients.
机译：背景：溶栓溶解（TA）是每次患者均在4.5小时内咨询患者突然局灶性神经缺陷的过程。目的：我们旨在首先确定TA的病因概况，其次是评估管理中管理的延迟，而不是溶栓的患者，也是非栓塞患者的延迟，以确定优化的内际延迟。方法：在4.5小时内咨询18岁以上的患者，涉及触发TA的4.5小时内的突发局灶性神经系统赤字。患者在4.5小时内尚未触发TA尚未触发。患有突然的局灶性神经缺陷患者，咨询了超过4.5小时，但也被触发了塔。结果：我们包括313名患者。平均入住门时间为125.59 +/- 62.78分钟，平均国家卫生学型卒中量表11.29 +/- 5.98。平均门上乘时间为28.36 +/- 20.62分钟。缺血性卒中（是）是最常见的原因（70.3％），其次是出血性中风（11.8％）。其他非行向原因（中风模拟）代表17.9％的病例。它们是癫痫发作（46.4％），转化障碍（26.8％），低血糖（10.7％），脑肿瘤（10.7％），慢性软骨血肿（1.8％），一氧化碳中毒（1.8％）和心肌瘤（1.8％） 。四十六名患者一直溶栓。平均门对针时间为90.89 +/- 34.48分钟。 3个月后，52.1％的溶栓患者是自主的（改进的Rankin规模在0到2之间）。两名患者死亡（4.3％），一直在第一周后。结论：我们的研究表明，需要在医院和医院内水平进行努力，以提高增加溶栓患者比例的延误。

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