• 主题
高级搜索  >
历史搜索 清空历史
首页> 外文期刊>Journal of stroke and cerebrovascular diseases: The official journal of National Stroke Association >The Contribution of Vascular Risk Factors in Prevalence of Fatigue Four Years Following Stroke: Results from a Population-Based Study
【24h】

The Contribution of Vascular Risk Factors in Prevalence of Fatigue Four Years Following Stroke: Results from a Population-Based Study

机译：血管危险因素在中风后四年患病患病率的贡献：基于人口的研究结果

获取原文
获取原文并翻译 | 示例
           
页面导航
  • 摘要
  • 著录项
  • 相似文献
  • 相关主题

摘要

Background: Fatigue is a debilitating symptom after stroke, which may persist for many years. Survivors of stroke commonly have comorbid medical conditions such as hypertension and diabetes mellitus that may produce fatigue by themselves. The contribution of vascular and other risk factors on long-term poststroke fatigue (PSF) has not been sufficiently investigated at a population-based level. Methods: Adults (N = 256) with stroke, who consented into the Auckland Regional Stroke Outcomes Study (ARCOS-IV), completed assessments including the Fatigue Severity Scale (FFS) at 4 years poststroke. A mean score greater than 4 was indicative of fatigue. A multiple regression model identified baseline associations (reported as adjusted odds ratio [AOR] with 95% confidence intervals [CI]) with long-term fatigue. Results: Fatigue was present in 141 stroke survivors (55%) 4 years after stroke, with a mean FSS score of 5.2 +/- 1.3. Having hypertension (AOR = 2.05, 95% CI: 1.05-3.99, P .05), diabetes mellitus (AOR = 2.15, 95% CI: 1.09-4.25, P .05), and arrhythmia (AOR = 3.01, 95% CI: 1.46-6.20, P .01) at the time of stroke were associated with increased PSF at 4 years. Nonvascular risk factors including female sex (AOR = 1.99, 95% CI: 1.06-03.70, P .05) and depression (AOR = 1.18, 95% CI: 1.01-1.39, P .05) were related to PSF. Conclusions: PSF was prevalent in the majority of survivors, with comorbid vascular factors significantly contributing to persistent fatigue. The implications of these findings are important as potentially modifiable factors can be targeted and treated from acute onset. Additional research examining PSF predictors in other populations and trialing targeted interventions to control predictors of PSF are warranted.
机译：背景：疲劳是中风后一种衰弱的症状，可能持续多年。中风的幸存者通常具有可同血管和糖尿病，如可能产生疲劳的高血压和糖尿病。血管和其他危险因素对长期失败疲劳（PSF）的贡献尚未在基于人群的水平上得到充分调查。方法：卒中成年人（N = 256），他同意奥克兰区域卒中成果研究（Arcos-IV），完成了4年后4年的疲劳严重程度（FFS）的评估。平均得分大于4表示疲劳。多元回归模型识别基线关联（报告为调整后的差距率[AOR]，具有长期疲劳的95％置信区间[CI]）。结果：141中风幸存者（55％）中疲劳存在于中风4年中，平均FSS得分为5.2 +/- 1.3。具有高血压（AOR = 2.05,95％CI：1.05-3.99，P＆ 05），糖尿病（AOR = 2.15,95％CI：1.09-4.25，P＆ .05），和心律失常（AOR = 3.01在中风时，95％CI：1.46-6.20，p＆ .01）与4年来的PSF增加。非血管危险因素，包括女性（AOR = 1.99,95％CI：1.06-03.70，P <0.05）和抑郁（AOR = 1.18,95％CI：1.01-1.39，P＆ 05）与PSF有关。结论：PSF在大多数幸存者中普遍存在，具有持续疲劳的合并血管因子。这些发现的影响是重要的，因为可能可修饰的因素可以从急性发作中靶向和治疗。需要额外的研究在其他群体中检测PSF预测因子，并试验目标干预控制PSF预测因子。

著录项

相似文献

  • 外文文献
  • 中文文献
  • 专利
获取原文

客服邮箱：kefu@zhangqiaokeyan.com

京公网安备：11010802029741号 ICP备案号：京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有

  • 客服微信

  • 服务号