...
  • 主题
高级搜索  >
历史搜索 清空历史
首页> 外文期刊>Journal of stroke and cerebrovascular diseases: The official journal of National Stroke Association >The Impacts of Peptic Ulcer on Stroke Recurrence
【24h】

The Impacts of Peptic Ulcer on Stroke Recurrence

机译：消化性溃疡对卒中复发的影响

获取原文
获取原文并翻译 | 示例
           
页面导航
  • 摘要
  • 著录项
  • 相似文献
  • 相关主题

摘要

Background: Peptic ulcer has been associated with an increased risk of stroke. This study aimed to evaluate the impacts of peptic ulcer on stroke recurrence and mortality. Subjects and Methods: Patients with first-ever ischemic stroke were retrospectively confirmed with or without a history of peptic ulcer. The primary end point was defined as fatal and nonfatal stroke recurrence. Risks of 1-year fatal and non-fatal stroke recurrence were analyzed with the Kaplan-Meier method. Predictors of fatal and nonfatal stroke recurrence were evaluated with the Cox proportional hazards model. Results: Among the 2577 enrolled patients with ischemic stroke, 129 (5.0%) had a history of peptic ulcer. The fatal and nonfatal stroke recurrence within 1 year of the index stroke was higher in patients with peptic ulcer than in patients without peptic ulcer (12.4% versus 7.2%, P = .030). Cox proportional hazards model detected that age (hazard ratio [HR] = 1.018, 95% confidence interval [CI] 1.005-1.031, P = .008), hypertension (HR =1.397, 95% CI 1.017-1.918, P = .039), and history of peptic ulcer (HR = 1.853, 95% CI 1.111-3.091, P = .018) were associated with stroke recurrence. Conclusions: Ischemic stroke patients with peptic ulcer may have an increased risk of stroke recurrence. The results emphasize the importance of appropriate prevention and management of peptic ulcer for secondary stroke prevention.
机译：背景：消化性溃疡已与中风的风险增加有关。本研究旨在评估消化性溃疡对卒中复发和死亡率的影响。受试者和方法：首次缺血中风的患者用或没有消化性溃疡的历史来回顾性证实。主要终点被定义为致命和非致卒中复发。用Kaplan-Meier方法分析了1年致命和非致命中风复发的风险。用Cox比例危害模型评估致命和非致卒中复发的预测因素。结果：2577名患有缺血性卒中的患者中，129（5.0％）有消化性溃疡的历史。患有消化性溃疡患者的指数中风后1年内的致命和非致卒中复发性比没有消化性溃疡的患者（12.4％，P = .030）。 Cox比例危害模型检测到年龄（危险比[HR] = 1.018，95％置信区间[CI] 1.005-1.031，P = .008），高血压（HR = 1.397,95％CI 1.017-1.918，P = .039 ）和消化性溃疡（HR = 1.853,95％CI 1.111-3.091，P = .018）的历史与中风复发有关。结论：缺血性溃疡患者可能具有增加的中风复发风险。结果强调了适当预防和治疗消化性溃疡的重要性次级中风预防。

著录项

  • 来源
  • 作者

    Xu Zongliang; Wang Ling; Lin Ying; Wang Zhaojun; Zhang Yun; Li Junrong; Li Shenghua; Ye Zusen; Yuan Kunxiong; Shan Wanying; Liu Xinfeng; Fan Xinying; Xu Gelin;

  • 作者单位

    Southern Med Univ Jinling Hosp Dept Neurol 305 East Zhongshan Rd Nanjing 210002 Jiangsu;

    Nanjing Univ Jinling Hosp Dept Neurol Sch Med Nanjing 210002 Jiangsu Peoples R China;

    Southern Med Univ Jinling Hosp Dept Neurol 305 East Zhongshan Rd Nanjing 210002 Jiangsu;

    Southern Med Univ Jinling Hosp Dept Neurol 305 East Zhongshan Rd Nanjing 210002 Jiangsu;

    Southern Med Univ Jinling Hosp Dept Neurol 305 East Zhongshan Rd Nanjing 210002 Jiangsu;

    Nanjing Med Univ Dept Neurol Jiangning Hosp Nanjing 211100 Jiangsu Peoples R China;

    Nanjing Med Univ Dept Neurol Jiangning Hosp Nanjing 211100 Jiangsu Peoples R China;

    Southern Med Univ Jinling Hosp Dept Neurol 305 East Zhongshan Rd Nanjing 210002 Jiangsu;

    Southern Med Univ Jinling Hosp Dept Neurol 305 East Zhongshan Rd Nanjing 210002 Jiangsu;

    Nanjing Univ Jinling Hosp Dept Neurol Sch Med Nanjing 210002 Jiangsu Peoples R China;

    Southern Med Univ Jinling Hosp Dept Neurol 305 East Zhongshan Rd Nanjing 210002 Jiangsu;

    Southern Med Univ Jinling Hosp Dept Neurol 305 East Zhongshan Rd Nanjing 210002 Jiangsu;

    Southern Med Univ Jinling Hosp Dept Neurol 305 East Zhongshan Rd Nanjing 210002 Jiangsu;

  • 收录信息
  • 原文格式 PDF
  • 正文语种 eng
  • 中图分类 神经病学与精神病学;
  • 关键词

    Peptic ulcer; ischemic stroke; recurrence; death;

    机译：消化性溃疡;缺血性卒中;复发;死亡;

相似文献

  • 外文文献
  • 中文文献
  • 专利
获取原文

客服邮箱：kefu@zhangqiaokeyan.com

京公网安备：11010802029741号 ICP备案号：京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有

  • 客服微信

  • 服务号