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首页> 外文期刊>Journal of stroke and cerebrovascular diseases: The official journal of National Stroke Association >The Prognostic Value of CT-Angiographic Parameters After Reperfusion Therapy in Acute Ischemic Stroke Patients With Internal Carotid Artery Terminus Occlusion: Leptomeningeal Collateral Status and Clot Burden Score
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The Prognostic Value of CT-Angiographic Parameters After Reperfusion Therapy in Acute Ischemic Stroke Patients With Internal Carotid Artery Terminus Occlusion: Leptomeningeal Collateral Status and Clot Burden Score

机译：急性缺血性中风末端闭塞症急性缺血性脑卒中患者再灌注治疗后CT-Anvoographic参数的预后价值：Leptomeningeal抵押状态和凝块负担得分

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BackgroundThe objective of this study was to investigate the prognostic value of computed tomographic angiography (CTA) based on leptomeningeal collateral (LMC) status and other parameters in acute ischemic stroke (AIS) patients with internal carotid artery (ICA) terminus occlusion treated with endovascular treatment (EVT). MethodsAll eligible patients from January 2013 to December 2017 undergoing EVT were retrospectively reviewed. The regional leptomeningeal score was used to assess the LMCs on baseline CTA. The collateral status measured by the LMC score (0-20) was trichotomized into 3 groups: good (17-20), intermediate (11-16), and poor (0-10). ResultsOur sample included a total of 119 eligible patients (60 males; mean age, 73 years) with a median baseline National Institute of Health Stroke Scale (NIHSS) score of 14. Patients with a good LMC score had a lower baseline mean NIHSS score, a higher mean Alberta Stroke Program Early CT score, and a higher mean clot burden score (CBS). Baseline NIHSS score <15 (odds ratio [OR] 3.69 95% confidence ratio [CI]: 1.32-10.29,P?=?.013), CBS ≥ 6 (OR 3.97 95%CI: 1.05-14.99,P?=?.042), good LMC score (OR 5.14 95%CI: 1.62-16.26,P?=?.005) and successful recanalization (OR 11.55 95%CI: 2.72-48.99P?=?.001) were independent predictors of good clinical outcomes. ConclusionsCTA-based LMC status and CBS are powerful predictors of clinical outcomes in patients with an acute ICA terminus occlusion treated with EVT.
机译：背景技术本研究的目的是探讨基于脑膜脑脑卒中（AIS）内部颈动脉（ICA）末端闭塞症（IIA）患者的髓鞘子副诊断（LMC）状态和其他参数的计算断层摄影血管造影（CTA）的预后价值（evt）。 MethableAllapard 2013年1月至2017年12月的符合条件的患者进行了回顾性审查。区域睑位评分用于评估基线CTA上的LMC。通过LMC评分（0-20）测量的抵押状态分为3组：良好（17-20），中间体（11-16）和差（0-10）。结果我们的样品包括共119名符合条件的患者（60名男性;平均年龄，73岁），中位数国家卫生冲程量表（NIHSS）评分为14分。良好的LMC评分患者具有较低的基线意味着NIHSS分数，艾伯塔省中风计划早期CT得分更高，均衡凝块负荷评分（CBS）更高。基线NIHSS得分<15（差距[或] 3.69 95％置信比[CI]：1.32-10.29，P？= 013），CBS≥6（或3.97 95％CI：1.05-14.99，P？=？ .042），良好的LMC评分（或5.14 95％CI：1.62-16.26，P？= 005）和成功的再生化（或11.55 95％CI：2.72-48.99p？= ?. 001）是良好的独立预测因素临床结果。结论基于的LMC状态和CBS是患有EVT处理的急性ICA末端闭塞患者临床结果的强大预测因子。

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