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首页> 外文期刊>Journal of stroke and cerebrovascular diseases: The official journal of National Stroke Association >Racial Difference in Cerebral Microbleed Burden Among a Patient Population in the Mid-South United States
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Racial Difference in Cerebral Microbleed Burden Among a Patient Population in the Mid-South United States

机译：南部中南患者人口中脑微微负担的种族差异

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BackgroundAlthough intracerebral hemorrhage (ICH) is more common among African-Americans, data on the burden of cerebral microbleeds (CMBs) among different races is limited. The purpose of this study is to compare the number, associated factors, and topography of CMBs between African-American and Caucasian populations in the Mid-South United States. MethodsUsing natural language processing, we extracted all brain MRIs performed during a 2-year period (2012-2013) when the report indicated the presence of CMB. All the extracted MRI studies were evaluated for number and location of CMBs, prior stroke, and deep white matter lesion. Negative binomial regression was used to model for the overdispersed count data. ResultsA total 167 patients (mean age was 63 ± 15?years, 49% men, 77% African-American, median CMB count: 8) with 1 or more CMBs on their brain MRI were included in this study. There was no significant difference between the 2 groups in terms of CMB locations (P= .086), but there was a significant difference between African-American and Caucasian patients in terms of number of CMBs (16.5 ± 18 versus 6.5 ± 5.5,P< .001). The prevalence of multiple CMBs (CMBs ≥ 5) was similar among African-Americans and Caucasians (72% versus 55%,P= .062). After adjusting for potential confounders, the African-American race was not independently associated with a higher CMB burden (P= .073). ConclusionAfrican-American race was not independently associated with a higher rate of CMB burden when compared to Caucasians after adjusting for potential confounders. We also did not observe a significant racial difference regarding the location and prevalence of multiple CMBs (CMBs ≥ 5).
机译：背景虽然脑出血（ICH）在非洲裔美国人中更常见，但不同种族中脑微杂种（CMBS）负担的数据有限。本研究的目的是比较非洲裔美国人和中南中美人群之间CMBS的数量，相关因素和地形。方法自然语言处理，我们提取了在报告表明CMB存在的情况下在2年期间（2012-2013）中进行的所有脑部MRI。评估所有提取的MRI研究，用于CMBS，先前中风和深白物质病变的数量和位置。负二项式回归用于模拟过量分散的计数数据。结果总共167名患者（平均年龄为63±15？年，49％的男性，77％的非洲裔美国人，中位数：8）在本研究中包含1个或更多CMBS的CMBS。 2组在CMB位置之间没有显着差异（P = .086），但非洲裔美国和高加索患者在CMB的数量方面存在显着差异（16.5±18对6.5±5.5，P <.001）。非洲裔美国人和高加索人和高加索人和高加索人和55％，P = .062的患病率相似。在调整潜在混乱之后，非洲裔美国人的比赛与更高的CMB负担没有独立相关（P = .073）。结案在调整潜在混凝徒后与高加索人相比，非洲裔美国人的比赛与高加索人相比，与白种人相比，与高加索人的负担较高。我们还没有观察到多个CMBS的位置和患病率的显着种族差异（CMBS≥5）。

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