...
  • 主题
高级搜索  >
历史搜索 清空历史
首页> 外文期刊>Journal of stroke and cerebrovascular diseases: The official journal of National Stroke Association >Risk of Stroke and Cardiac Events in Medically Treated Asymptomatic Carotid Stenosis
【24h】

Risk of Stroke and Cardiac Events in Medically Treated Asymptomatic Carotid Stenosis

机译：中风和心脏事件的风险在医学上治疗的无症状颈动脉狭窄

获取原文
获取原文并翻译 | 示例
           
页面导航
  • 摘要
  • 著录项
  • 相似文献
  • 相关主题

摘要

Background: The risk of stroke in patients with 50% or more asymptomatic carotid stenosis (ACS) on intensive medical treatment is low. Hence, the optimal treatment of ACS remains controversial at this point of time. Aim: We assessed the risk of stroke/transient ischemic attack (TIA) and cardiac events in patients with 50% or more ACS on intensive medical treatment. Methods: All patients with TIA/minor stroke (National Institutes of Health Stroke Scale score <= 5) who had undergone vessel imaging as part of their evaluation and patients with coronary artery disease who had undergone vessel imaging before cardiac intervention were screened for the presence of asymptomatic carotid stenosis. The risk of TIA/stroke, cardiac events, and vascular deaths were evaluated. Results: Of 1,800 patients, 92 patients (.05%) had ACS having 50% to 99% stenosis; 63 had TIA/minor stroke, and 29 had coronary artery disease, of whom 7 patients had bilateral ACS, thus constituting 99 study units of ACS. The mean follow-up was 34.7 months (range 3-120 months). Two patients developed ischemic events on the side ipsilateral to the ACS and 9 patients developed cardiac events during the follow-up. The average annual event rate for cerebral ischemic events was .93% (95% confidence interval [CI], .11-3.37), 4.21% (95% CI, 1.92-7.98) for cardiac events, and 3.27% (95% CI, 1.31-6.74) for death. Conclusions: Although the risk of stroke in patients with ACS is low, acute coronary events and vascular deaths were significant. This highlights the importance of intensive risk factor modification to reduce adverse cardiovascular events in ACS rather than revascularization of the carotid stenosis. (C) 2015 by National Stroke Association
机译：背景：患有50％或更多无症状颈动脉狭窄（ACS）的患者中风的风险低。因此，在这一刻，AC的最佳治疗仍然存在争议。目的：我们评估了在强化医疗的50％或更多ACS患者中卒中/短暂性缺血性发作（TIA）和心脏事件的风险。方法：所有TIA /轻微中风的患者（国家卫生卒中量表得分<= 5），他们作为其评估的一部分和冠心病患者在心脏干预之前进行了血管成像的血管成像的一部分，筛选出存在无症状颈动脉狭窄。评估TIA /中风，心脏事件和血管死亡的风险。结果：1,800名患者，92例患者（0.05％）的狭窄率为50％至99％; 63有TIA / mins卒中，29例冠状动脉疾病，其中7名患者具有双侧ACS，因此构成了99个ACS的研究单位。平均随访时间为34.7个月（范围3-120个月）。两名患者在IPSILATAL侧面发育了缺血事件，对ACS和9名患者在随访期间开发了心脏事件。脑缺血事件的平均事件率为.93％（95％置信区间[CI]，.11-3.37），4.21％（95％CI，1.92-7.98），适用于3.27％（95％CI ，1.31-6.74）死亡。结论：虽然ACS患者中风的风险是低的，但急性冠状动脉事件和血管死亡是显着的。这突显了强烈风险因素修饰的重要性，以减少ACS中的不良心血管事件而不是颈动脉狭窄的血运重建。 （c）2015年国家冲程协会

著录项

相似文献

  • 外文文献
  • 中文文献
  • 专利
获取原文

客服邮箱：kefu@zhangqiaokeyan.com

京公网安备：11010802029741号 ICP备案号：京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有

  • 客服微信

  • 服务号