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首页> 外文期刊>Journal of stroke and cerebrovascular diseases: The official journal of National Stroke Association >Detection and Predictors of Paroxysmal Atrial Fibrillation in Acute Ischemic Stroke and Transient Ischemic Attack Patients in Singapore
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Detection and Predictors of Paroxysmal Atrial Fibrillation in Acute Ischemic Stroke and Transient Ischemic Attack Patients in Singapore

机译：新加坡急性缺血性卒中和短暂性缺血患者阵发性心房颤动的检测与预测

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Background: Detection of paroxysmal atrial fibrillation (pAF) is important for optimal secondary stroke prevention. Data are limited from Asia regarding inpatient occurrence and predictors of pAF to optimize electrocardiographic (ECG) monitoring despite it having nearly two thirds of the world's population and different subtypes of stroke from the West. Methods: We analyzed a prospective dataset comprising 370 acute ischemic stroke (AIS) and 25 transient ischemic attack (TIA) patients without known atrial fibrillation who underwent continuous ECG monitoring (CEM) in an acute stroke unit from July 2012 to February 2013. The median duration of monitoring was 61 hours. Results: There were 31 cases of pAF. The detection rate was 8% for both AIS and TIA patients. It occurred less often in lacunar infarcts (3%) compared to nonlacunar infarcts (10%) (P = .047). The detection rates in cryptogenic infarcts (10%) and infarcts of known causes (7%) were not significantly different (P = .224). The predictors of pAF according to logistic regression were hemorrhagic conversion (P = .006), scattered infarcts (P = .007), radiological cardiomegaly (P = .007), occlusion of symptomatic artery (P = .023), and older age (P < .001). Conclusions: pAF occurred in 8% of AIS and TIA in a hospitalized cohort of Asian patients. All patients without known atrial fibrillation should undergo CEM for at least 3 days during hospitalization and priority given to patients with predictors of pAF in centers with resource constraints.
机译：背景：阵发性心房颤动（PAF）的检测对于最佳的继发性卒中预防是重要的。尽管有近三分之二的世界人口和来自西方的中风不同亚型患者，但是，数据有关PAF的住院发生和预测因素的限制，以优化心电图（ECG）监测。方法：我们分析了一份未知的急性缺血性卒中（AIS）和25例瞬时缺血性脑卒中（TIA）患者的前瞻性数据集，没有已知的心房颤动，他们于2012年7月至2013年2月在急性中风单元中进行了连续的ECG监测（CEM）。中位数监测持续时间为61小时。结果：PAF有31例。 AIS和TIA患者的检出率为8％。与非裂变梗死（10％）相比，它在Levunar Infarcts（3％）中较少发生（p = .047）。密码发生梗死（10％）和已知原因（7％）的梗塞的检测率没有显着差异（p = .224）。 PAF的预测因子根据逻辑回归是出血性转化（p = .006），散射梗塞（p = .007），放射性心脏肿大（p = .007），闭塞症状动脉（p = .023）和老年人（p <.001）。结论：PAF在8％的AIS和TIA中发生在住院群体的亚洲患者。所有没有已知心房颤动的患者应在住院期间至少3天进行CEM，优先考虑PAF预测因子的患者，以资源限制为中心。

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