...
  • 主题
高级搜索  >
历史搜索 清空历史
首页> 外文期刊>Journal of stroke and cerebrovascular diseases: The official journal of National Stroke Association >Ischemic and Hemorrhagic Strokes due to Eosinophilic Granulomatosis with Polyangiitis
【24h】

Ischemic and Hemorrhagic Strokes due to Eosinophilic Granulomatosis with Polyangiitis

机译：由于嗜酸性粒细胞粒细胞芽孢杆菌病患性缺血性和出血性脑卒中

获取原文
获取原文并翻译 | 示例
           
页面导航
  • 摘要
  • 著录项
  • 相似文献
  • 相关主题

摘要

Background: We report a case of ischemic and hemorrhagic strokes occurring almost simultaneously in a patient diagnosed with eosinophilic granulomatosis with polyangiitis (EGPA) previously known as Churg-Strauss vasculitis. To our knowledge, this is the first known case. Methods: A 59-year-old man presented with a 2-month history of bilateral leg weakness, difficulty ambulating, and dyesthesias. While in the hospital, he developed acute right hand weakness, and magnetic resonance imaging of the brain revealed multiple, bilateral ischemic infarcts. After a few days, he acutely became unresponsive and was found to have a large left frontal hematoma and underwent emergent hematoma evacuation. His weakness was unexplained by the infarcts based on location and so a peripheral process was suspected. Results: Nerve conduction studies showed severe axonal sensorimotor neuropathy. A sural nerve biopsy showed necrotizing vasculitis, consistent with EGPA. Conclusions: EGPA is the rarest of the antineutrophilic cytoplasmic antibody vasculitides. The peripheral nervous system is frequently involved, but the central nervous system can also be affected. The vasculitis damages the vessel walls, which leads either to stenosis or to dilatation, resulting in ischemic or bleeding consequences which can occur simultaneously, such as in this case. Caution should be exercised when prescribing antiplatelet therapy to such patients.
机译：背景：我们在诊断患有先前称为Churg-Strauss血管炎的嗜酸性粒细胞粒细胞瘤病患者的患者中出现了几乎同时发生的缺血性和出血式中风的情况。为了我们的知识，这是第一个已知的案例。方法：一名59岁的男子介绍了2个月的双边腿部弱势历史，难以挥动和染色。在医院的同时，他发育了急性右手的弱点，并且大脑的磁共振成像显示出多种双边缺血性梗塞。几天后，他急剧无响应，被发现有一个大的左前血肿和接受突出的血肿疏散。他的弱点是基于位置的梗塞未解释，因此怀疑外周过程。结果：神经传导研究显示严重的轴突索感运动员神经病变。血管神经活检显示坏死性血管炎，与EGPA一致。结论：EGPA是抗逆制细胞质抗体血管谱的最稀有。周围神经系统经常涉及，但中枢神经系统也可能受到影响。血管炎损坏了血管壁，导致狭窄或扩张，导致缺血性或出血后果，其可以同时发生，例如在这种情况下。应在向这些患者处方抗血小板疗法时谨慎行事。

著录项

相似文献

  • 外文文献
  • 中文文献
  • 专利
获取原文

客服邮箱：kefu@zhangqiaokeyan.com

京公网安备：11010802029741号 ICP备案号：京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有

  • 客服微信

  • 服务号