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Metabolic Syndrome in Polish Ischemic Stroke Patients

机译:波兰缺血性卒中患者的代谢综合征

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Background: Metabolic syndrome (MetS) predisposes individuals to cardiovascular disease or stroke development. We aimed at evaluating the prevalence of MetS in a population of acute ischemic stroke (IS) patients from central Poland and at estimating the relationship between MetS and stroke risk. Methods: We analyzed 672 IS patients who were consecutively admitted to stroke units. The control group was composed of 612 patients with other neurologic disorders. MetS was diagnosed if 3 of 5 factors were present (obesity, increased blood pressure, increased triglycerides, low high-density lipoprotein [HDL] cholesterol, and fasting hyperglycemia) according to the Unified Criteria for Clinical Diagnosis of the Metabolic Syndrome (2009). Results: MetS was diagnosed in 61.2% of stroke patients versus 18.1% of the control group (P < .001). Multiple logistic regression showed that MetS was 1.8 times more common in women than in men (odds ratio [OR], 1.8; 95% confidence interval [CI], 1.4-2.5). The adjusted OR (95% CI) associated with MetS was 2.44 (1.48-3.64; P < .001) for IS. Hypertension and hypertriglyceridemia were the most frequent disturbances of IS patients (87.2% and 68.2%, respectively). The analysis of the interaction between MetS and its components showed significant associations with hypertension (OR, 2.15; 95% CI,.98-4.24; P < .01), high triglyceride levels (OR, 4.35; 95% CI, 2.87-9.43; P < .0001), and low HDL cholesterol levels (OR, 5.12; 95% CI, 3.15-8.20; P < .001). Conclusions: Over 60% of Polish IS patients have MetS. The prevalence of MetS was significantly higher in women than in men. Thus, MetS may be a risk factor for IS. (C) 2015 by National Stroke Association
机译:背景:代谢综合征(METS)倾向于个人心血管疾病或中风发育。我们旨在评估来自波兰中部的急性缺血性卒中(IS)患者的患者的患病率,估计大都会和卒中风险之间的关系。方法:我们分析了672谁被连续收治卒中单元的患者。对照组由612名其他神经系统障碍组成。根据统一标准,如果存在5个因素(肥胖,血压,增加甘油三酯,低高密度脂蛋白,低高密度脂蛋白[HDL]胆固醇和禁食高血糖症),则诊断出METS。结果:METS诊断为61.2%的中风患者,对照组的18.1%(P <.001)。多元逻辑回归显示,女性在女性中的常见额度比男性更常见(赔率比[或],1.8; 95%置信区间[CI],1.4-2.5)。与MET相关的调整后的或(95%CI)为2.44(1.48-3.64; p <.001)。高血压和高甘油脂血症是患者最常见的紊乱(分别为87.2%和68.2%)。对Mets及其组分之间的相互作用分析显示出具有高血压的显着关联(或2.15; 95%CI,0.98-4.24; P <.01),高甘油三酯水平(或4.35; 95%CI,2.87-9.43 ; p <.0001)和低HDL胆固醇水平(或5.12; 95%CI,3.15-8.20; P <.001)。结论:超过60%的抛光剂是患者已经满足。女性的Mets患病率明显高于男性。因此,METS可能是危险因素。 (c)2015年国家冲程协会

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