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首页> 外文期刊>Journal of stroke and cerebrovascular diseases: The official journal of National Stroke Association >Inverse Relationship between Coffee Consumption and Cerebral Microbleeds in Men, but Not Women
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Inverse Relationship between Coffee Consumption and Cerebral Microbleeds in Men, but Not Women

机译：咖啡消费与男性脑脊布之间的反向关系，但不是女性

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摘要

Background: Studies evaluating the association between coffee consumption and neurovascular diseases have frequently yielded contradictory results. The aim of this study was to investigate the association of coffee consumption with small-vessel disease (SVD) incidence in a healthy urban population while accounting for multiple demographic and lifestyle risk factors. Methods: This prospective study conducted from May 2013 through March 2014 included 455 participants (314 men and 141 women) aged 25 to 92 years. All subjects completed a questionnaire on coffee consumption and received a comprehensive neurologic examination, including magnetic resonance imaging, at St. Luke's International Hospital (Tokyo, Japan). Results: Incidence of SVD was lower in male daily coffee drinkers than male nondrinkers and occasional drinkers, whereas incidence of white matter lesions was lower in female daily coffee drinkers than female nondrinkers or occasional drinkers. In multivariate analyses including age, sex, smoking status, and BMI, as well as coffee consumption, incidence of microbleeds was significantly lower in male daily coffee drinkers compared to nondrinkers. Conclusions: Daily coffee consumption is associated with reduced risk of cerebral microbleeds in men.
机译：背景：研究评估咖啡消耗和神经血管疾病之间的关系经常产生矛盾的结果。本研究的目的是调查咖啡消费与小血管疾病（SVD）发病率的咖啡消费协会，同时考虑多种人口和生活方式风险因素。方法：2013年5月至2014年3月的这项未来研究包括455名参与者（314名男子和141名妇女），年龄在25至92岁。所有受试者在圣卢克国际医院（日本东京，日本东京）完成了咖啡消费的问卷并获得了综合性神经系统检查，包括磁共振成像，包括磁共振成像。结果：男性日常咖啡饮用者的SVD发病率低于男性不良饮用者，而白质病变的发生率比女性每日咖啡饮用者低于女性非产品或偶尔的饮酒者。在包括年龄，性别，吸烟状态和BMI的多变量分析中，以及咖啡消费，与非产品相比，男性日常咖啡饮用者的发病率显着降低。结论：日常咖啡消费与男性脑微微肌肤风险降低有关。

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