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首页> 外文期刊>Journal of stroke and cerebrovascular diseases: The official journal of National Stroke Association >Diagnosis of Hyperlipidemia and Treatment With a Statin in the Outpatient Stroke Clinic
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Diagnosis of Hyperlipidemia and Treatment With a Statin in the Outpatient Stroke Clinic

机译：高脂血症的诊断和门诊卒中诊所的汀类药物治疗

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The aim of this study was to assess a stroke clinic's performance in the diagnosis of hyperlipidemia and more specifically to evaluate the effectiveness of statins in patients with cerebrovascular disease not enrolled in a research study. The records of 370 consecutive patients seen at a stroke clinic over a 4-year period were reviewed, and information regarding neurologic diagnosis, lipid profile, and use and type of cholesterol-lowering medication was abstracted. Hyperlipidemia was defined as a total cholesterol level equal to or more than 200 mg/dL. Forty-eight patients meeting specific criteria were further analyzed to monitor the effects of statins. Cholesterol testing was obtained in 324 patients (88%) and 178 (55%) were hyperlipidemic, but only 86 (48%) patients received treatment. The mean cholesterol level of the 48 patients dropped from 246.2 mg/dL to 197.1 mg/dL (P < .0001) after the initiation of statin therapy, and significant reductions were present in subgroups with pretreatment levels of 200 to 249 mg/dL and 250 to 299 mg/dL. Of the 21 patients with repeated cholesterol testing more than 6 months after the first posttreatment test, only 11 (52%) maintained a level below 200 mg/dL. Effective control of hyperlipidemia can be achieved in patients with cerebrovascular disease, but not all are adequately tested or treated. Improved physician awareness and more effective health care delivery systems are needed.
机译：本研究的目的是评估卒中诊所在诊断高脂血症中的表现，更具体地说，评估患有脑血管病患者的患者未纳入研究研究的患者的有效性。综述了370名卒中诊所的370名患者的记录，并提出了有关神经诊断，脂质型材和使用以及胆固醇降低药物类型的信息。高脂血症定义为总胆固醇水平等于或大于200mg / dL的总胆固醇水平。进一步分析48名符合特定标准的患者，以监测他汀类药物的影响。在324名患者（88％）和178名（55％）中获得胆固醇测试是高脂质化，但只有86例（48％）患者接受治疗。 48名患者的平均胆固醇水平从246.2mg / dl到197.1mg / dl（p <0001）在他汀类药物治疗开始后从246.2 mg / dl（p <.0001）下降，并且在亚组中存在显着的降低，预处理水平为200至249 mg / dl和250至299 mg / dl。在第一次胆固醇测试的21例患者中，在第一次后处理试验后超过6个月，只有11（52％）保持低于200mg / dl的水平。脑血管病患者可以实现高脂血症的有效控制，但并非所有的测试或治疗都不能够实现。需要改善医师意识和更有效的医疗保健系统。

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