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首页> 外文期刊>Journal of stroke and cerebrovascular diseases: The official journal of National Stroke Association >Risk Factors for Acute Heart Failure and Impact on In-Hospital Mortality after Stroke
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Risk Factors for Acute Heart Failure and Impact on In-Hospital Mortality after Stroke

机译：急性心脏衰竭的危险因素及中风后院内死亡的影响

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Background: In the acute phase of stroke, some patients develop cardiac events. It could be fatal in their clinical courses. We aimed to investigate acute heart failure after stroke onset and stratify the patients by establishing a predictive model. Methods: This single-center, observational study included stroke patients diagnosed at the Department of Neurology and Neurosurgery from January 2013 to December 2014. Baseline characteristics and clinical findings on admission were analyzed for acute heart failure after stroke. We assessed risk factors using multivariable logistic regression, and set a risk score to evaluate the association with poor outcomes. Results: Of 532 stroke patients, 27 (5%) developed acute heart failure within the 7 days after admission. We identified 4 risk factors for acute heart failure after stroke: atrial fibrillation (odds ratio [OR], 5.9; 95% confidence interval [CI], 2.5-14.0; P<.001), history of cardiac disease (OR, 3.6; 95% CI, 1.3-9.1; P=.01), Glasgow Coma Scale score <= 8 (OR, 4.5; 95% CI, 1.7-12.0; P=.003), and serum albumin<35 g/L (OR, 3.4; 95% CI, 1.4-8.4; P=.008). Furthermore in-hospital mortality rate was higher (37% [n=10/27] versus 9.9% [n=50/505], P=.001) in patients with poststroke heart failure. Higher predictive scores were associated with increased mortality. Conclusions: Acute heart failure can develop in the early phase of stroke and lead to poor outcomes. It is foreseeable and preventable by stratifying and monitoring high-risk patients.
机译：背景：在中风的急性期，一些患者发展心脏事件。在他们的临床课程中可能是致命的。我们旨在通过建立预测模型来研究中风发作后的急性心力衰竭并分层。方法：该单中心，观察研究包括从2013年1月到2014年1月诊断出在神经病学和神经外科患者诊断的中风患者。卒中后急性心力衰竭分析基线特征和临床调查。我们评估了使用多变量逻辑回归的风险因素，并设定风险分数，以评估与差的结果相关联。结果：532例卒中患者，27例（5％）在入院后7天内发育急性心力衰竭。我们鉴定了中风后急性心力衰竭的4个危险因素：心房颤动（差距率[或]，5.9; 95％置信区间[CI]，2.5-14.0; p <.001），心脏病的历史（或3.6; 95％CI，1.3-9.1; p = .01），Glasgow Coma Scale得分<= 8（或4.5; 95％CI，1.7-12.0; p = .003），以及血清白蛋白<35 g / l（或，3.4; 95％CI，1.4-8.4; p = .008）。此外，在外心故障失败的患者中，医院中的死亡率较高（37％[n = 10/27]，p = .001）。更高的预测性分数与增加的死亡率相关。结论：急性心力衰竭可以在卒中的早期发展，导致结果不佳。通过分层和监测高风险患者可预见并预防。

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