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首页> 外文期刊>Journal of stroke and cerebrovascular diseases: The official journal of National Stroke Association >Application of Neck Circumference in Four-Variable Screening Tool for Early Prediction of Obstructive Sleep Apnea in Acute Ischemic Stroke Patients
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Application of Neck Circumference in Four-Variable Screening Tool for Early Prediction of Obstructive Sleep Apnea in Acute Ischemic Stroke Patients

机译：颈周在急性缺血性卒中患者梗阻性睡眠呼吸暂停早期预测中的应用

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Background: The purpose of this study was to validate and pilot the use of the four-variable screening tool (4V) and modified 4V tools to identify acute ischemic stroke and transient ischemic attack (TIA) patients at high risk of obstructive sleep apnea (OSA). Methods: Two modified scales, 4V-1 (ie, using neck circumference instead body mass index, regardless of gender) and 4V-2 (ie, as above but scored differently according to gender) were designed. These tools were used in a consecutive cohort of 124 acute ischemic stroke/TIA patients, together with the 4V-1, 4V-2, 4V, as well as the STOP-BANG, the Berlin questionnaire, and the Epworth Sleepiness Scale (ESS). Objective level 2 or level 3 polysomnography was used to confirm OSA and its severity. Both questionnaires and polysomnography were completed within 1 week from symptom onset. Results: Area under the curve (AUC) of 4V was 0.807 (P < .0001) while AUC of STOP-BANG, Berlin Questionnaire and ESS were .701 (P < .0001), .704 (P < .0001) and .576 (P = .1556), respectively. AUC of 4V was greater than of STOP-BANG (z = 2.200, P = .0220), Berlin (z = 2.024, P = .0430) and ESS (z = 3.363, P = .0003). AUC of modified 4V-1 and modified 4V-2 were .824 (P < .001) and .835 (P < .001), respectively. Performance of modified 4V-2 was higher versus modified 4V-1 (z = 2.111, P = .0348) and higher but not significantly so to regular 4V (z = 1.784, P = .0744). Conclusions: Neck circumference scored by gender is a useful substitution to body mass index in the 4V when screening OSA at early stages of ischemic stroke/TIA patients.
机译：背景：本研究的目的是验证和试验使用四种可变筛选工具（4V）和改性的4V工具，以鉴定急性缺血性卒中和瞬时缺血性发作（TIA）患者，患有高风险睡眠呼吸暂停（OSA ）。方法：设计了两个改进的鳞片，4V-1（即，使用颈圆周代替体重指数，无论性别）和4V-2（即，如上所述，但根据性别等等）。这些工具以124名急性缺血性卒中/ TIA患者的连续队列使用，以及4V-1,4V-2，4V，以及止际，柏林问卷和欧洲呼吸睡眠等级（ESS） 。目标2级或3级多瘤摄影术用于确认OSA及其严重程度。问卷和多面体摄影都在症状发作后1周内完成。结果：4V曲线下的面积为0.807（P <.0001），而停止爆炸，柏林问卷和ESS的AUC均为.701（P <.0001），.704（P <.0001）和。分别为576（p = .1556）。 4V的AUC大于STOP-BANG（Z = 2.200，P = .0220），柏林（Z = 2.024，P = .0430）和ESS（Z = 3.363，P = .0003）。修饰的4V-1和改性的4V-2的AUC分别为0.824（P <.001）和.835（P <.001）。改性的4V-2的性能与修饰的4V-1（Z = 2.111，P = .0348）和更高但不明显地为常规4V（Z = 1.784，P = .0744）。结论：当在缺血性卒中/ TIA患者的早期阶段筛查OSA时，性别评分的颈部周周长是在4V时对体重指数的有用替代。

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