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首页> 外文期刊>Journal of Structural Biology >THREE-DIMENSIONAL RECONSTRUCTION FROM REDUCED SETS OF VERY NOISY IMAGES ACQUIRED FOLLOWING A SINGLE-AXIS TILT SCHEMA - APPLICATION OF A NEW THREE-DIMENSIONAL RECONSTRUCTION ALGORITHM AND OBJECTIVE COMPARISON WITH WEIGHTED BACKPROJECTION
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THREE-DIMENSIONAL RECONSTRUCTION FROM REDUCED SETS OF VERY NOISY IMAGES ACQUIRED FOLLOWING A SINGLE-AXIS TILT SCHEMA - APPLICATION OF A NEW THREE-DIMENSIONAL RECONSTRUCTION ALGORITHM AND OBJECTIVE COMPARISON WITH WEIGHTED BACKPROJECTION

机译：单轴倾斜模式下获取的减少的非常嘈杂图像的三维重建 - 应用新的三维重建算法和加权反投影的客观比较

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In this work we propose a reconstruction algorithm (ART with blobs) that has not been previously used in electron Tomography and we compare it with the standard method in the field (weighted back projection, WBP). We assume that only a limited set of very noisy images, collected around a single axis tilt, is available; which is a typical situation in Electron Tomography. In general, the reconstruction problem is underdetermined (due to the limited number of projections) and the data are inconsistent (due to the high level of noise). The evaluation of the results is performed in a rigorous way by a task-oriented approach which makes use of numerical observers. ART with blobs outperforms WBP for a number of key tasks. Results are presented both for simplified line integral data and for realistic simulations of macromolecular structures embedded in amorphous ice. (C) 1997 Academic Press. [References: 21]
机译：在这项工作中，我们提出了一种预先用于电子断层扫描的重建算法（具有BLOB的艺术），并将其与现场中的标准方法进行比较（加权后投影，WBP）。 我们假设只有一个有限的非常嘈杂的图像，可以在单轴倾斜周围收集; 这是电子断层扫描中的典型情况。 通常，重建问题是未确定的（由于数量有限的投影），并且数据不一致（由于高水平的噪声）。 结果的评估以严谨的方式通过由数值观察者使用的任务导向的方法进行。 艺术与Blobs的艺术胜过WBP的许多关键任务。 结果表明，用于简化的线路积分数据和嵌入无定形冰的大分子结构的现实模拟。 （c）1997年学术出版社。 [参考：21]

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