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首页> 外文期刊>Journal of substance abuse treatment >Medical cannabis use among patients with chronic pain in an interdisciplinary pain rehabilitation program: Characterization and treatment outcomes
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Medical cannabis use among patients with chronic pain in an interdisciplinary pain rehabilitation program: Characterization and treatment outcomes

机译：跨学科疼痛康复计划中慢性疼痛患者的医疗大麻使用：表征和治疗结果

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Abstract Introduction Cannabis is increasingly being used in the treatment of chronic pain. However, there is a lack of available research in the population of patients with chronic pain who are using cannabis. The current study examines clinical and treatment characteristics for patients who are admitted to a 3-week outpatient interdisciplinary chronic pain rehabilitation program. Method Participants ( N = 48) included patients with a positive urine drug screen for 9-carboxy-tetrahydrocannabinol (THC(+); n = 24) and a matched comparison sample of patients with a negative screen (THC(?); n = 24). Participants were matched for age, gender, race, education, and current prescription opioid use. Measures of pain, functioning, and quality of life were completed at admission and discharge. Medical chart review was conducted to assess medication and substance use history. Results Participants with a positive screen for THC were more likely to report a past history of illicit substance use, alcohol abuse, and current tobacco use. Cannabis use was not associated with a significantly lower morphine equivalence level for participants using prescription opioids ( n = 14). Both groups of participants reported significant improvement in pain severity, pain interference, depressive symptoms, and pain catastrophizing. There were no group- or treatment-related differences in these outcome variables. Discussion Results provide preliminary evidence that patients with chronic pain using cannabis may benefit from an interdisciplinary chronic pain program. Patients with chronic pain using cannabis may be at higher risk for substance-related negative outcomes, although more research is needed to understand this relationship. Highlights ? Patients using cannabis report benefit from a pain rehabilitation program. ? Patients in both the THC and non-THC groups showed improved pain-related adjustment outcomes upon completion of the program. ? There were no group differences between THC and non-THC users at discharge. ? Patients using cannabis may present higher baseline risk for substance use problems.
机译：摘要介绍大麻越来越多地用于治疗慢性疼痛。然而，在使用大麻的慢性疼痛患者患者中缺乏可用的研究。目前的研究检查了患者入住3周门诊跨学慢性疼痛康复计划的患者的临床和治疗特征。方法参与者（n = 48）包括患有9-羧基 - 四氢胺（Thc（+）; n = 24）的阳性尿液药筛网的患者，以及阴性筛网的患者的匹配比较样本（thc（？）; n = 24）。参与者与年龄，性别，种族，教育和当前的处方表阿片类药物相匹配。在入场和出院完成疼痛，运作和生活质量的措施。进行了医疗图表评估以评估药物和物质使用历史。结果THC积极屏幕的参与者更有可能报告过去的非法物质使用，酒精滥用和目前烟草使用的历史。使用处方阿片类药物（n = 14），大麻使用与参与者的大规模对吗啡当量水平无关。两组参与者均报告疼痛严重程度，疼痛干扰，抑郁症状和疼痛灾难性的显着改善。这些结果变量没有群体或治疗相关的差异。讨论结果提供了使用大麻慢性疼痛的患者可以从跨学科慢性疼痛计划中受益。虽然需要更多的研究来了解这种关系，但使用大麻慢性疼痛的患者可能处于较高的实质负面结果的风险。强调 ？患者使用大麻报告的痛苦康复计划受益。还在计划完成后，THC和非THC组中的患者显示出改善的疼痛相关的调整结果。还THC和非THC用户在放电时没有组差异。还使用大麻的患者可能为物质使用问题呈现更高的基线风险。

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