...
  • 主题
高级搜索  >
历史搜索 清空历史
首页> 外文期刊>Journal of substance abuse treatment >The effectiveness of nicotine patch and nicotine lozenge in very heavy smokers.
【24h】

The effectiveness of nicotine patch and nicotine lozenge in very heavy smokers.

机译：尼古丁补丁和尼古丁锭剂在非常重的吸烟者中的有效性。

获取原文
获取原文并翻译 | 示例
           
页面导航
  • 摘要
  • 著录项
  • 相似文献
  • 相关主题

摘要

The efficacy of nicotine replacement therapy (NRT) among very heavy and highly dependent smokers was examined in a secondary analysis of two randomized clinical trials of NRT. In the first trial, smokers were assigned to active patch (n=249) or placebo (n=253) plus intensive behavioral treatment. In the second trial, smokers were assigned to active 4-mg nicotine lozenge (n=450) or placebo (n=451) plus brief behavioral treatment. Nicotine patch and lozenge significantly increased 6-month continuous abstinence quit rates in both very heavy (>or=40 cigarettes per day) and highly dependent (Fagerstrom Tolerance Questionnaire or Fagerstrom Test for Nicotine Dependence score >7) smokers. The effect of active NRT treatment did not differ significantly by smoking rate or nicotine dependence, with the exception that the nicotine patch was significantly more effective than placebo in highly dependent smokers. The nicotine patch and lozenge are effective (vs. placebo) even in heavy and highly dependent smokers.
机译：在NRT的两种随机临床试验的二次分析中，研究了尼古丁替代疗法（NRT）在非常重和高度依赖的吸烟者中的疗效。在第一次试验中，将吸烟者分配给有源贴片（n = 249）或安慰剂（n = 253）加密行为治疗。在第二次试验中，将吸烟者分配给活性4-mg尼古丁锭剂（n = 450）或安慰剂（n = 451）加上短暂的行为治疗。尼古丁补丁和锭剂在非常重的（>或= 40支卷烟）和高度依赖（Fagerstrom耐受调查问卷或尼古丁依赖评分Scomatience Score> 7）吸烟者中的6个月连续禁止戒烟率显着增加了6个月的连续禁止戒烟率。活性NRT治疗的效果在吸烟率或尼古丁依赖性并没有显着差异，但除了尼古丁贴剂在高度依赖的吸烟者中明显比安慰剂更有效。尼古丁贴剂和锭剂即使在沉重和高度依赖的吸烟者中也是有效的（与安慰剂）。

著录项

相似文献

  • 外文文献
  • 中文文献
  • 专利
获取原文

客服邮箱：kefu@zhangqiaokeyan.com

京公网安备：11010802029741号 ICP备案号：京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有

  • 客服微信

  • 服务号