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首页> 外文期刊>Journal of the Academy of Nutrition and Dietetics >Nutrition Assessment in Crohn's Disease using Anthropometric, Biochemical, and Dietary Indexes: A Narrative Review
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Nutrition Assessment in Crohn's Disease using Anthropometric, Biochemical, and Dietary Indexes: A Narrative Review

机译：使用人体测量，生化和饮食指标的克罗恩病中营养评估：叙事评论

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摘要

Malnutrition is common in patients with Crohn's disease and negatively influences immunity and quality of life. The optimal tools for nutrition assessment in patients with Crohn's disease are not clearly defined and lead to variations in practice. With this review, we aimed to appraise the existing evidence for nutrition assessment of patients with Crohn's disease compared with healthy controls and provide a comprehensive guide with relevant measures applicable to clinical practice. A literature search using Medline, Embase, and Scopus from inception to October 1, 2018, was conducted. Forty-one articles that assessed body composition, muscle strength, micronutrient status and/or dietary intake in adults with Crohn's disease compared with an age- and sex-matched healthy individuals were included. There were heterogeneous findings on nutritional status in patients with Crohn's disease compared with healthy controls. Only one article reported a clinically significant difference for body mass index; however, significant deficits in fat mass, fat-free mass, and muscle strength were observed in patients with Crohn's disease compared with healthy controls, with more pronounced differences with increasing disease activity and length of diagnosis. Most research reported significantly lower serum micronutrients in patients with Crohn's disease compared with healthy controls. Half of studies measuring micronutrient intake reported lower intakes in patients with Crohn's disease compared with healthy controls. Fruit and vegetable intake was also lower in patients with Crohn's disease. Difficulties characterizing the type and prevalence of malnutrition exist due to the heterogeneous nature of Crohn's disease and warrants continued investigation. As a result of this review, we advocate that a nutrition assessment should include more parameters than weight and body mass index.
机译：营养不良是克罗恩病的患者常见，对抗免疫力和生活质量产生负面影响。克罗恩病患者营养评估的最佳工具没有明确定义并导致实践中的变化。通过本综述，我们的旨在评估培养患者培养评估的现有证据与健康控制相比，并提供了一个适用于临床实践的相关措施的综合指南。在2018年10月1日开始使用Medline，Embase和Scopus的文献搜索。包括四十一篇文章，评估身体成分，肌肉力量，微量营养素及/或膳食摄入与Crohn疾病相比的成年人与年龄和性别匹配的健康个体相比。与健康对照相比，克罗恩病患者营养状况有异质结果。只有一篇文章报告了体重指数的临床显着差异;然而，与健康对照相比，患者患者患者患有脂肪质量，无脂肪块和肌肉力量的显着缺陷，患疾病活动增加和诊断长度更加明显差异。与健康对照相比，大多数研究报告称克罗恩病患者患者血清微量营养素显着降低。测量微量营养素摄入量的一半研究报告了克罗恩病患者的摄入量与健康对照相比。克罗恩病的患者患者也降低了水果和植物摄入量。由于克罗恩疾病的异质性质，表征营养不良类型和患病率的困难，并持续调查。由于本综述，我们倡导营养评估应包括比体重和体重指数更多的参数。

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