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Fundamentals of Lung Cancer Staging

机译:肺癌分期基础

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Lung cancer is the leading cause of cancer-related mortality in the United States and the world. The treatment of non-small cell lung cancer (NSCLC) is dependent on adequate staging of disease at diagnosis. Computed tomography (CT) and positron emission tomography-computed tomography (PET/CT) provide noninvasive evaluation of the extent of disease. These may be the extent of staging in the case of stage IV disease. However, earlier stages of NSCLC require more extensive surgical staging evaluation. In the past 10 years, minimally invasive procedures utilizing endoscopic and video-assisted techniques have provided the ability to obtain precise staging, with a decrease in cost and morbidity associated with prior invasive procedures, such as mediastinoscopy. Each technique provides information needed for full classification and staging. The American Joint Committee on Cancer tumor-node-metastasis (TNM) staging system is updated regularly to estimate prognosis and selection of appropriate therapy. This review will discuss the staging techniques and classifications necessary to guide the management of patients with newly diagnosed lung cancer.
机译:肺癌是美国和世界癌症相关死亡的主要原因。非小细胞肺癌(NSCLC)的治疗取决于诊断时足够的疾病分期。计算机断层扫描(CT)和正电子发射断层摄影 - 计算机断层扫描(PET / CT)提供了对疾病程度的非侵略性评估。这些可能是阶段IV疾病的暂存程度。然而,NSCLC的早期阶段需要更广泛的手术分期评估。在过去的10年中,利用内窥镜和视频辅助技术的微创程序已经提供了获得精确分期的能力,其成本和发病率降低了与现有侵入性手术,例如含有常膜镜检查。每种技术都提供完整分类和分期所需的信息。美国癌症肿瘤节点转移(TNM)分期系统的联合委员会定期更新,以估计预后和选择适当的治疗。本综述将讨论指导新诊断肺癌患者管理所需的分期技术和分类。

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