Li-Fraumeni Syndrome

WENDY H. VOGEL

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Li-Fraumeni Syndrome

机译：l i-Frau么你syndrome

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Li-Fraumeni syndrome is a rare inherited autosomal-dominant disorder that is manifested by a wide range of malignancies that appear at an unusually early age. Li-Fraumeni syndrome is also known as sarcoma, breast, leukemia, and adrenal gland (SBLA) cancer syndrome. This syndrome first appeared in the medical literature around 1969 (Li & Fraume-ni, 1969a, 1969b). Other malignancies associated with this syndrome include malignancies of the lung, pancreas, skin, gastrointestinal tract, choroid plexus, and germ cell, as well as lymphoma, early-onset colorectal cancer, and Wilms tumor (Agarwal et al., 2014).

机译：李弗拉梅尼综合征是一种罕见的遗传性常染色体显性障碍，表现出广泛的恶性肿瘤，这些恶性肿瘤呈现出异常的早期性。李弗拉梅尼综合征也被称为肉瘤，乳腺，白血病和肾上腺（SBLA）癌症综合征。该综合症于1969年的医学文献中出现（Li＆Fraume-Ni，1969A，1969B）。与此综合征相关的其他恶性肿瘤包括肺，胰腺，皮肤，胃肠道，脉络丛和生殖细胞的恶性肿瘤，以及淋巴瘤，早发结直肠癌和威尔斯肿瘤（Agarwal等，2014）。

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《Journal of the advanced practitioner in oncology》 |2017年第7期|共5页
作者
WENDY H. VOGEL;
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Wellmont Cancer Institute Kingsport Tennessee;

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正文语种 eng
中图分类肿瘤学;
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机译：儿童新型畸形突变的同步恶性的情况：这是锂弗拉梅尼综合征还是伪装成李弗劳曼尼综合征的新案例？
6. The psychosocial effects of the Li-Fraumeni Education and Early Detection (LEAD) program on individuals with Li-Fraumeni syndrome [J] . Ross Jessica, Bojadzieva Jasmina, Peterson Susan, Genetics in medicine . 2017,第9期

机译：李 - 弗拉梅尼综合征李 - 弗拉梅尼教育及早期检测（领导）计划的心理社会影响
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机译：研究使用循环肿瘤DNA进行癌症监测和早期检测（儿科）肉瘤和Li-Fraumeni综合征
10. The Psychosocial Effects of the Li-Fraumeni Education and Early Detection (LEAD) Program on Individuals with Li-Fraumeni Syndrome [O] . Jessica Ross, Jasmina Bojadzieva, Susan Peterson, -1

机译：Li-Fraumeni综合征早期诊断和早期检测（LEAD）计划对个体的心理社会影响
11. The psychosocial effects of the Li-Fraumeni Education and Early Detection (LEAD) program on individuals with Li-Fraumeni syndrome [O] . Jessica Ross, Jasmina Bojadzieva, Susan Peterson, 2017

机译：李弗劳明教育与早期检测（铅）对锂呋喃氏综合征的个体的心理社会影响

Li-Fraumeni Syndrome

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