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Herbal Product Contamination and Toxicity

机译：草药产品污染和毒性

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Herbal poisoning exposures reported to poison centers increased by 344% after passage of the Dietary Supplement Health and Education Act, with 24412 exposures reported in 2003. Increased toxicity is speculated to be related to lack of child-resistant packaging, new issues of contamination, proliferation of multiple ingredient products, excessive concentration of active ingredients, and discovery of new drug-herb interactions. This review addresses contamination issues such as heavy metals, pharmaceuticals, homeopathic remedies, microbes, insects, environmental chemicals, and misidentification of one plant for another. Toxicity issues covered include carcinogenicity, delay in seeking medical treatment when usingherbs to treat serious illness, toxic components, hypersensitivity reactions, hepatotoxins, nephro-toxins, epileptogenic compounds, cardiac toxins, gastrointestinal toxins, and hematologic toxins. Common drug-herb interactions are discussed. The pharmacist plays an important role in patient education and evaluation of potential toxicities related to herbal supplements.
机译：膳食补充卫生和教育法案后，毒药中心报告的草药中毒暴露在膳食补充卫生和教育法案中提高了344％，2003年报告了24412次暴露。拟议毒性增加，缺乏患有儿童包装，污染问题的新问题有关，毒性多种成分产物，过度浓度的活性成分，以及新药草相互作用的发现。该审查涉及污染问题，如重金属，药品，顺势疗法疗法，微生物，昆虫，环境化学品和另一个植物的误诊。涉及的毒性问题包括致癌性，延迟寻求医疗时的药物治疗严重疾病，有毒成分，过敏反应，肝毒素，肾毒素，癫痫化合物，心脏毒素，胃肠毒素和血液学毒素。讨论了常见的药草互动。药剂师在患者教育和对草药补充剂相关的潜在毒性的评估中起着重要作用。

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