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首页> 外文期刊>Journal of the American Academy of Dermatology >Humanistic burden of chronic pruritus in patients with inflammatory dermatoses: Results of the European Academy of Dermatology and Venereology Network on Assessment of Severity and Burden of Pruritus (PruNet) cross-sectional trial
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Humanistic burden of chronic pruritus in patients with inflammatory dermatoses: Results of the European Academy of Dermatology and Venereology Network on Assessment of Severity and Burden of Pruritus (PruNet) cross-sectional trial

机译:炎症皮肤患者慢性瘙痒的人文负担:欧洲皮肤病学与经济网络研究结果评估瘙痒症(PRUNET)横截面试验

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BackgroundChronic pruritus is a multifactorial, challenging symptom of global relevance. ObjectiveThe European Academy of Dermatology and Venereology Network on Assessment of Severity and Burden of Pruritus (PruNet) investigation aimed to analyze the severity and humanistic burden of chronic pruritus in patients suffering from inflammatory dermatoses across Europe. MethodsProspectively collected routine data on 552 patients (with atopic dermatitis, contact dermatitis, prurigo nodularis, psoriasis vulgaris, lichen planus, or mycosis fungoides [pruritus numeric rating scale score ≥3]) from 9 European centers (in Austria, France, Germany, Italy, Poland, Russia, Spain, Switzerland, and Turkey) were analyzed by univariate and multivariate variance analyses of various itch characteristics and quality of life (as measured by the Dermatology Life Quality Index and the ItchyQoL). ResultsDuration, frequency, and intensity of pruritus (according to a numeric rating scale and visual analog scale) and related impairment of quality of life differed between European centers and dermatologic diagnoses (P?
机译:BackgroundChronic Pruritus是一个多因素,挑战全球相关性的症状。欧洲皮肤病学院和经呼网络评估瘙痒症的严重程度和负担的评估旨在分析欧洲患有炎症皮肤病患者慢性瘙痒的严重程度和人文负担。 PhotoftyProspective地收集了552名患者的常规数据(具有特应性皮炎,接触皮炎,瘙痒症,牛皮癣,地衣,地衣平面或肌瘤诱导率≥3])来自9个欧洲中心(在奥地利,法国,德国,意大利,波兰,俄罗斯,西班牙,瑞士和土耳其分析了各种瘙痒特征和生活质量的单变量和多元差异分析(如皮肤科生活质量指数和Itchyqol)。瘙痒(根据数字评定标度和视觉模拟规模)的结果,频率和强度,欧洲中心和皮肤病诊断的生活质量相关的相关损伤(P?<β.05)。该中心所在的国家对患者评估瘙痒强度和寿命质量而不是诊断(p?<〜001)的影响。包括每个国家的限制中心。结论炎症皮肤患者慢性瘙痒症的人文负担高。欧洲跨文化因子可能比特异性皮肤病诊断更强烈的影响力诊断瘙痒患者的瘙痒和生活质量的强度。

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