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首页> 外文期刊>Journal of the American Academy of Dermatology >Human oncoviruses: Mucocutaneous manifestations, pathogenesis, therapeutics, and prevention Hepatitis viruses, human T-cell leukemia viruses, herpesviruses, and Epstein-Barr virus
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Human oncoviruses: Mucocutaneous manifestations, pathogenesis, therapeutics, and prevention Hepatitis viruses, human T-cell leukemia viruses, herpesviruses, and Epstein-Barr virus

机译：人的卵巢病毒：粘整体表现，发病机制，治疗和预防肝炎病毒，人T细胞白血病病毒，疱疹病毒和彭斯坦 - 巴尔病毒

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摘要

In 1964, the first human oncovirus, Epstein-Barr virus, was identified in Burkitt lymphoma cells. Since then, 6 other human oncoviruses have been identified: human papillomavirus, Merkel cell polyomavirus, hepatitis B and C viruses, human T-cell lymphotropic virus-1, and human herpesvirus-8. These viruses are causally linked to 12% of all cancers, many of which have mucocutaneous manifestations. In addition, oncoviruses are associated with multiple benign mucocutaneous diseases. Research regarding the pathogenic mechanisms of oncoviruses and virus-specific treatment and prevention is rapidly evolving. Preventative vaccines for human papillomavirus and hepatitis B virus are already available. This review discusses the mucocutaneous manifestations, pathogenesis, diagnosis, treatment, and prevention of oncovirus-related diseases. The first article in this continuing medical education series focuses on diseases associated with human papillomavirus and Merkel cell polyomavirus, while the second article in the series focuses on diseases associated with hepatitis B and C viruses, human T-cell lymphotropic virus-1, human herpesvirus-8, and Epstein-Barr virus.
机译：1964年，在Burkitt淋巴瘤细胞中鉴定了第一个人类动物孢子病毒，Epstein-Barr病毒。从那时起，已鉴定出6种其他人的细胞病毒：人乳头瘤病毒，梅尔克尔细胞多马病毒，乙型肝炎和C病毒，人T细胞淋巴细胞病毒-1和人疱疹病毒-8。这些病毒因所有癌症的12％而导致导致，其中许多具有粘整体表现。此外，子宫病毒与多种良性粘膜皮肤病有关。关于细胞病毒和病毒特异性治疗和预防的病原机制的研究是迅速发展的。已经提供了人乳头瘤病毒和乙型肝炎病毒的预防疫苗。本综述讨论了与病毒相关疾病的霉菌表现，发病机制，诊断，治疗和预防。该持续医学教育系列的第一篇文章侧重于与人乳头瘤病毒和Merkel细胞多马病毒相关的疾病，而该系列中的第二篇文章侧重于与乙型肝炎和C病毒相关的疾病，人类T细胞淋巴细胞病毒-1，人疱疹病毒-8和epstein-barr病毒。

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