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首页> 外文期刊>Journal of the American Academy of Nurse Practitioners. >Fatty liver in adolescents on the U.S.-Mexico border.
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Fatty liver in adolescents on the U.S.-Mexico border.

机译：在美国 - 墨西哥边境的青少年的脂肪肝。

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PURPOSE: To describe the physical and metabolic characteristics of children diagnosed with fatty liver disease in a gastroenterology clinic in El Paso, Texas. DATA SOURCES: A retrospective chart review of 31 patients aged 8-18 diagnosed with fatty liver was conducted. CONCLUSIONS: These children were diagnosed with fatty liver by elevated alanine aminotransferase (ALT) levels (mean ALT levels 126 +/- 08 U/L) and increased hepatic echogenicity measured via ultrasound. The majority of children were adolescents (12-17 years of age) and Mexican American. All subjects were overweight (body mass index [BMI] > or = 95th percentile) based on Centers for Disease Control and Prevention standards. In a subset of children for whom results from laboratory test were available, we found 40% had high triglycerides (> or = 150 mg/dL), 53% had low high-density lipoprotein cholesterol (< or = 35 mg/dL), and 17% had prediabetes (fasting glucose > or = 100 mg/dL). The clinical and laboratory findings in this patient population with fatty liver are consistent with a diagnosis of nonalcoholic fatty liver disease (NAFLD). IMPLICATIONS FOR PRACTICE: Despite the increasing trend in overweight among children and adolescents, data suggest low rates of diagnosis and management of overweight and related comorbidities by healthcare providers. Overweight has been associated with fatty liver disease in the pediatric population and includes other comorbidities such insulin resistance and features of metabolic syndrome. Screening for overweight in children should constitute the first step in identifying children at risk for NAFLD. Nurse practitioners should include in the evaluation of pediatric patients calculation of BMI and waist circumference for age and screening for other overweight-related comorbidities.
机译：目的：描述德克萨斯州El Paso肠道诊所患有脂肪肝病的儿童的物理和代谢特征。数据来源：对31例患者诊断患有脂肪肝诊断的31例患者的回顾图综述。结论：通过升高的丙氨酸氨基转移酶（ALT）水平（平均ALT水平126 +/- 08 U / L）和通过超声测量的增加的肝脏回声，这些儿童被诊断患有脂肪肝。大多数孩子是青少年（12-17岁）和墨西哥美国人。基于疾病控制和预防标准的中心，所有受试者均超重（体重指数[BMI]>或= 95位）。在可获得实验室试验结果的儿童的子集中，我们发现40％具有高甘油三酯（>或= 150mg / dl），53％具有低高密度脂蛋白胆固醇（<或= 35mg / dl）， 17％的前奶油（空腹葡萄糖>或= 100mg / dL）。这种患者患有脂肪肝的临床和实验室结果与非酒精性脂肪肝病（NAFLD）的诊断一致。对实践的影响：尽管儿童和青少年之间超重呈现了越来越大，但数据建议通过医疗保健提供者对超重和相关的合并症的诊断和管理率低。超重与儿科人群中的脂肪肝病有关，包括其他胰岛素抵抗和代谢综合征的特征。对儿童超重的筛选应该构成识别NAFLD风险风险的儿童的第一步。护士从业者应包括评估儿科患者的BMI和腰围的年龄和筛选其他超重相关的合并症。

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