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首页> 外文期刊>Journal of the history of the neurosciences >The Sherrington-Cushing connection: A bench to bedside collaboration at the dawn of the twentieth century
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The Sherrington-Cushing connection: A bench to bedside collaboration at the dawn of the twentieth century

机译：Sherrington-Cushing连接：在二十世纪黎明的床上合作

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摘要

British physiologist Charles Sherrington (1857-1952) and American neurosurgeon Harvey Cushing (1869-1939) were seminal figures in the history of neuroscience. The two came from different worlds, one laboratory-based and the other largely clinical. Their scientific intersection, beginning in July 1901, provides a glimpse into a nascent form of "bench to bedside" collaboration, which carried with it the potential to extend the arm of neurophysiological experimentation from Sherrington's laboratory to Cushing's operatory. I reviewed extensive primary source materials archived at Yale University School of Medicine Library. Sherrington viewed Cushing's bedside work as an opportunity, in humans, to extend his bench-side physiological observations on higher primates, at times almost directing Cushing in the clinic. Cushing would indeed take Sherrington's observations on apes and extend them to his patients, and the work would eventually overturn the prevailing notion that the motor and sensory cortex were intermixed across the Rolandic fissure.
机译：英国生理学家Charles Sherrington（1857-1952）和美国神经外科哈维库彭（1869-1939）是神经科学史上的开创性人物。这两个来自不同的世界，一个基于实验室和另一个主要的临床。他们的科学交叉口于1901年7月开始，将一瞥为“卧板到床边”合作的闪闪发光，这是延长了延长了Sherrington的实验室的神经生理实验的臂，从而延长了库欣的稳定性。我审查了广泛的主要源材料，在耶鲁大学医学图书馆存档。 Sherrington在人类中观看了Cushing的床边工作，以延长高级灵长类动物的长凳侧的生理观察，有时几乎在临床中指导缓冲。 Cushing确实将采取Sherrington对猿的观察，并将其延伸给他的患者，并且工作最终将推翻电机和感官皮质在罗兰德裂缝中混合的普遍观念。

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