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首页> 外文期刊>Journal of the European Academy of Dermatology and Venereology: JEADV >Systemic therapy of ocular and cutaneous rosacea in children
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Systemic therapy of ocular and cutaneous rosacea in children

机译：儿童眼镜和皮肤混凝土的全身治疗

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Abstract Background In paediatric rosacea, ocular symptoms are often predominant. Literature about systemic therapy of paediatric ocular rosacea is sparse, though. Objective Analysis of children with ocular rosacea treated systemically, particularly addressing remission and recurrence rates. Methods Retrospective study reviewing the medical records of children with ocular rosacea treated with systemic antibiotic therapy. Nine of 19 patients were chosen for detailed analysis. To our knowledge, this is the first study in paediatric ocular rosacea requiring systemic therapy with a larger patient group and a longer follow‐up (mean follow‐up = 30.2 months). Results 17 patients (89.5%) suffered from blepharitis, 15 patients (78.9%) from conjunctivitis, twelve patients (63.2%) from chalazia/styes and nine female patients (47.4%) from corneal involvement. We used erythromycin ( n = 9) or roxithromycin ( n = 1) in patients younger than 8 years and doxycycline ( n = 8) or minocycline ( n = 1) in patients older than 8 years. Seven of nine patients treated with erythromycin, one of eight patients treated with doxycycline and the patient treated with minocycline achieved a complete remission of ocular and cutaneous symptoms. Two of nine patients treated with erythromycin, seven of eight patients treated with doxycycline and the patient treated with roxithromycin achieved a partial remission. Relapses occurred in the patient treated with minocycline (cutaneous), two of eight patients treated with doxycycline (ocular and cutaneous) and one of nine patients treated with erythromycin (cutaneous). Conclusion To achieve a complete remission of cutaneous and ocular rosacea, a long‐term anti‐inflammatory treatment of at least 6 months is necessary. The relapse rates seem to be lower than in adults especially in the patients treated with erythromycin.
机译：在儿科小儿rosacea的抽象背景，眼镜症状通常是主要的。然而，关于儿科眼睑肌瘤的系统性治疗的文献稀疏。物理分析患有眼部玉米饼的儿童全身治疗，特别是解决缓解和复发率。方法回顾性研究综述患有全身抗生素治疗患有眼部蔷薇痤疮儿童的病程。选择九个患者进行详细分析。为了我们的知识，这是需要具有较大患者组的全身治疗的儿科眼罗西菌和更长的随访（平均随访= 30.2个月）研究。结果17例患者（89.5％）患有睑炎，15名患者（78.9％）来自Chexunctia / styes和九个女性患者（47.4％）的联膜炎，12名患者（63.2％）。在8岁以上的患者中，我们使用了超过8岁和12岁（N = 8）或米诺环素（n = 1）的患者的红霉素（n = 9）或罗西霉素（n = 1）。九个患者患有七种患者，用红霉素治疗，其中八名患者中的八个患者中的一项，含有米诺环素治疗的患者取得了完全缓解了眼部和皮肤症状。用红霉素治疗的九名患者，八个患者患有八个患者中的7例，并用罗西霉素治疗的患者达到了部分缓解。用米诺环素（皮肤）治疗的患者发生在患者中，八名患者中的两种患者中有两种患者治疗，其中含有红霉素（皮肤和皮肤）治疗的九个患者之一。结论为了实现皮肤和眼部Rosacea的完全缓解，需要至少6个月的长期抗炎治疗。复发率似乎低于成年人，特别是在用红霉素治疗的患者中。

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