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首页> 外文期刊>Journal of the Medical Association of Thailand =: Chotmaihet thangphaet >Prevalence and factors associated with left ventricular systolic dysfunction in end-stage renal disease patients on dialysis
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Prevalence and factors associated with left ventricular systolic dysfunction in end-stage renal disease patients on dialysis

机译：透析末期肾病患者左心室收缩功能障碍相关的患病率和因素

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? 2016, Medical Association of Thailand. All rights reserved. ? 2016, Medical Association of Thailand. All rights reserved. Background: Heart failure is a major cause of morbidity and mortality in patients with end-stage renal disease (ESRD). Previous studies reported various factors associated with left ventricular systolic dysfunction (LVSD) in patients with ESRD. Objective: To investigate the prevalence and factors associated with LVSD in patients with ESRD on dialysis. Material and Method: Patients with ESRD on dialysis who underwent comprehensive transthoracic echocardiography at Siriraj Hospital between 2003 and 2014 were enrolled. LVSD was defined as left ventricular ejection fraction less than 40%. Results: One hundred sixty one patients with a mean age of 56.5±15.4 years were included and 46% were female. Regarding mode of dialysis, 25% and 75% of patients were on peritoneal dialysis and hemodialysis, respectively. Median duration of dialysis was three years. Smoking, diabetes, dyslipidemia, and hypertension were reported in 30%, 40%, 57%, and 94% of patients, respectively. History of heart failure and coronary artery disease (CAD) were reported in 23% and 24% of cases, respectively. Prevalence of LVSD was 5%. History of heart failure, known CAD, and left ventricular diastolic dimension (LVDd) were found to be univariately associated with LVSD. Multivariate factors associated with LVSD were known CAD (OR 23.67, 95% CI 1.23-456.54, p-value = 0.036) and LVDd (OR 1.56, 95% CI 1.15-2.11, p-value = 0.004). Conclusion: Prevalence of LVSD in patients with ESRD on dialysis in the present study was 5%. Known CAD and LVDd were independent predictors of LVSD in this population. Background: Heart failure is a major cause of morbidity and mortality in patients with end-stage renal disease (ESRD). Previous studies reported various factors associated with left ventricular systolic dysfunction (LVSD) in patients with ESRD. Objective: To investigate the prevalence and factors associated with LVSD in patients with ESRD on dialysis. Material and Method: Patients with ESRD on dialysis who underwent comprehensive transthoracic echocardiography at Siriraj Hospital between 2003 and 2014 were enrolled. LVSD was defined as left ventricular ejection fraction less than 40%. Results: One hundred sixty one patients with a mean age of 56.5±15.4 years were included and 46% were female. Regarding mode of dialysis, 25% and 75% of patients were on peritoneal dialysis and hemodialysis, respectively. Median duration of dialysis was three years. Smoking, diabetes, dyslipidemia, and hypertension were reported in 30%, 40%, 57%, and 94% of patients, respectively. History of heart failure and coronary artery disease (CAD) were reported in 23% and 24% of cases, respectively. Prevalence of LVSD was 5%. History of heart failure, known CAD, and left ventricular diastolic dimension (LVDd) were found to be univariately associated with LVSD. Multivariate factors associated with LVSD were known CAD (OR 23.67, 95% CI 1.23-456.54, p-value = 0.036) and LVDd (OR 1.56, 95% CI 1.15-2.11, p-value = 0.004). Conclusion: Prevalence of LVSD in patients with ESRD on dialysis in the present study was 5%. Known CAD and LVDd were independent predictors of LVSD in this population.
机译：还2016年，泰国的医学协会。版权所有。还2016年，泰国的医学协会。版权所有。背景：心力衰竭是患有末期肾病（ESRD）的患者发病率和死亡率的主要原因。以前的研究报告了与ESRD患者患者的左心室收缩功能障碍（LVSD）相关的各种因素。目的：探讨透析透析患者ESRD患者患有LVSD的患病率和因素。材料与方法：2003年至2014年间锡拉拉医院综合静态超声心动图的透析患者入学。 LVSD定义为左心室喷射分数小于40％。结果：一百六十一年均为56.5±15.4岁的患者，女性为46％。关于透析模式，分别为25％和75％的患者分别对腹膜透析和血液透析。透析持续时间为三年。患有30％，40％，57％和94％的患者的吸烟，糖尿病，血脂性血症和高血压分别报告。报告了心力衰竭和冠状动脉疾病（CAD）分别以23％和24％的病例报告。 LVSD的患病率为5％。发现心力衰竭，已知的CAD和左心室舒张尺寸（LVDD）与LVSD无序。已知与LVSD相关的多变量因子CAD（或23.67,95％CI 1.23-456.54，P值= 0.036）和LVDD（或1.56,95％CI 1.15-2.11，P值= 0.004）。结论：本研究中透析患者LVSD患者的患病率为5％。已知的CAD和LVDD是LVSD的独立预测因子。背景：心力衰竭是患有末期肾病（ESRD）的患者发病率和死亡率的主要原因。以前的研究报告了与ESRD患者患者的左心室收缩功能障碍（LVSD）相关的各种因素。目的：探讨透析透析患者ESRD患者患有LVSD的患病率和因素。材料与方法：2003年至2014年间锡拉拉医院综合静态超声心动图的透析患者入学。 LVSD定义为左心室喷射分数小于40％。结果：一百六十一年均为56.5±15.4岁的患者，女性为46％。关于透析模式，分别为25％和75％的患者分别对腹膜透析和血液透析。透析持续时间为三年。患有30％，40％，57％和94％的患者的吸烟，糖尿病，血脂性血症和高血压分别报告。报告了心力衰竭和冠状动脉疾病（CAD）分别以23％和24％的病例报告。 LVSD的患病率为5％。发现心力衰竭，已知的CAD和左心室舒张尺寸（LVDD）与LVSD无序。已知与LVSD相关的多变量因子CAD（或23.67,95％CI 1.23-456.54，P值= 0.036）和LVDD（或1.56,95％CI 1.15-2.11，P值= 0.004）。结论：本研究中透析患者LVSD患者的患病率为5％。已知的CAD和LVDD是LVSD的独立预测因子。

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