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首页> 外文期刊>Journal of veterinary cardiology >Echocardiographic indices of age- and gender-dependent cardiac remodeling over the adult lifespan in Irish Wolfhounds
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Echocardiographic indices of age- and gender-dependent cardiac remodeling over the adult lifespan in Irish Wolfhounds

机译：在爱尔兰狼群中成年寿命的年龄和性别依赖性心脏反射的超声心动图索引

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IntroductionCharacterizing age- and gender-dependent cardiac remodeling over the adult lifespan in Irish Wolfhounds (IWs) by echocardiography. In people, a life-long cardiac remodeling process has been demonstrated.Animals, materials, methodsIrish Wolfhounds (56 males, 90 females) with no indication of cardiac disease at final assessment (>7.0 years old). For each dog, four transthoracic echocardiographic studies were analyzed. Left ventricular (LV) systolic and diastolic internal dimensions (LVIDs, LVIDd), LV fractional shortening (FS) and ejection fraction (EF), LV free wall and interventricular septal thickness, right ventricular diastolic dimension, and left atrial (LA) and right atrial systolic diameters were compared at time points in the following age categories (years): 1.0–2.5; 3.0–4.0; 4.5–6.0; and 7.0–10.5?and related to age, body weight, and heart rate.ResultsOver the adult life course, males had statistically significant increases in LV internal dimensions, atrial diameters, and decreases of FS and EF. From youngest to oldest age of examination means?±?standard deviations were as follows: LVIDs, 32.7?±?2.9 vs. 36.5?±?2.9?mm; LVIDd, 49.6?±?4.7 vs. 53.4?±?3.8?mm; right atrial diameter, 36.8?±?3.3 vs. 42.6?±?3.3?mm; LA, 49.0?±?3.6 vs. 55.0?±?3.7?mm; and FS, 34.6?±?3.7 vs. 31.0?±?3.2. In females, LV internal dimensions did not change significantly, increases in right atrial (38.1?±?3.7?mm to 40.0?±?5.2?mm) and LA diameter (48.8?±?3.6 to 52.4?±?4.3?mm) were attenuated, as were decreases of FS (33.4?±?3.7 to 31.5?±?4.4,p?=?0.02). LV wall thicknesses did not significantly change in both genders.Discussion and conclusionsOver the adult life course, echocardiography demonstrated increasing LV dimensions in male IWs only. In both genders, FS and EF decreased, and atrial diameters increased. Females showed an attenuated remodeling process.
机译：通过超声心动图术语引导特征依赖于年龄和性别依赖性心脏重塑成人羊路（IWS）的成人寿命。在人们中，已经证明了生命长的心脏重塑过程。动物，材料，方法狼犬（56名男性，90名女性），无表明在最终评估（> 7.0岁）。对于每只狗，分析了四种进行了四种进行了ransthoracic超声心动图。左心室（LV）收缩系统和舒张式内部尺寸（LVID，LVIDD），LV分数缩短（FS）和射血分数（EF），LV自由壁和间歇性间隔厚度，右心室舒张尺寸和左心房（LA）和右侧在以下年龄类别（年）的时间点比较心房收缩直径（年）：1.0-2.5; 3.0-4.0; 4.5-6.0;和7.0-10.5？和年龄，体重和心率相关。结果成人寿命课程，雄性在统计上显着增加了LV内部尺寸，心房直径和FS和EF的减少。从最年轻的考试年龄意味着？±标准偏差如下：LVID，32.7？±2. 2.9与36.5？±2.9？mm; lvidd，49.6？±4.7与53.4？±3.8？mm;右心房直径，36.8？±3.3与42.6？±3.3？mm; La，49.0？±3.6与55.0？±3.7？mm;和fs，34.6？±3.7与31.0？±3.2。在雌性中，LV内部尺寸没有显着变化，右心房（38.1？±3.7〜40.0？±5.2？mm）和La直径（48.8？±3.6至52.4？±4.3？mm）衰减，如FS减少（33.4？±3.7至31.5？±4.4，P？= 0.02）。两种性别都没有显着变化。讨论和结论成年生命课程，超声心动图仅表明了雄性IWS中的LV尺寸增加。在两个人的性别，FS和EF减少，心房直径增加。女性显示出衰减的重塑过程。

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