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Exposure to firework chemicals from production factories in pregnant women and risk of preterm birth occurrence in Liuyang, China

机译:从孕妇生产工厂接触烟花化学品以及中国浏阳早产的风险

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摘要

In the production of fireworks, various pollutants including particles of metals and organic compounds are released into the environment. Although the adverse effects of these air pollutants are known, the impact on pregnant women residing in this area remains to be determined. The aim of this study was to examine the association between maternal exposure to fireworks production chemicals and frequency of preterm birth in Liuyang, China. Maternal exposure to fireworks production was estimated at the residential district level and assessed using factory density, which was defined as the number of fireworks factories per 1000 residents in each district. The association of maternal exposure to particulates released from fireworks production plants with frequency of preterm birth was determined using data obtained from a cohort study conducted in Liuyang, China. Data were analyzed utilizing linear regression and logistic regression. There was no significant association between factory density and spontaneous preterm or medically induced preterm birth. Unexpectedly, pregnant women residing in areas with higher density of fireworks factories were at a reduced risk of preterm premature rupture of membranes (PPROM). Data demonstrated that residential density of fireworks factories appeared to be negatively correlated with preterm birth rate as evidenced by PPROM. At present, it is difficult to reconcile the inverse relationship between firework chemical exposure and frequency of preterm births as ambient particulate inhalation is known to adversely affect preterm birth occurrence.
机译:在烟花的生产中,包括金属颗粒和有机化合物的各种污染物被释放到环境中。尽管这些空气污染物的不利影响是已知的,但仍然确定对贫困妇女的影响仍有待确定。本研究的目的是审查母体接触烟花生产化学品和中国浏阳早产的频率之间的关联。母亲接触烟花生产估计在住宅区级别估计,并使用工厂密度评估,该工厂密度被定义为每个地区每隔1000名居民的烟花工厂数量。使用从中国六阳在中国的队列研究中获得的数据获得的数据确定母体暴露于从烟花生产植物释放的颗粒释放的颗粒。利用线性回归和逻辑回归分析数据。工厂密度和自发早产或医学诱导的早产之间没有显着关联。出乎意料的是,留在烟花厂密度较高的地区的孕妇处于降低预破坏性膜(PPROM)的风险。数据表明,烟花工厂的住宅密度似乎与PPROM证明的早产率呈负相关。目前,难以调和烟花化学曝光与早产频率之间的反向关系,因为已知环境颗粒状吸入对早产出生发生不利影响。

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    Cent S Univ Xiangya Hosp Dept Obstet Changsha Hunan Peoples R China;

    Cent S Univ Xiangya Sch Publ Hlth Dept Epidemiol &

    Hlth Stat Changsha Hunan Peoples R China;

    Cent S Univ Xiangya Sch Publ Hlth Dept Epidemiol &

    Hlth Stat Changsha Hunan Peoples R China;

    Cent S Univ Xiangya Sch Publ Hlth Dept Epidemiol &

    Hlth Stat Changsha Hunan Peoples R China;

    Cent S Univ Xiangya Sch Publ Hlth Dept Epidemiol &

    Hlth Stat Changsha Hunan Peoples R China;

    Liuyang Municipal Hosp Maternal &

    Child Hlth Dept Obstet Liuyang Hunan Peoples R China;

    Cent S Univ Xiangya Sch Publ Hlth Dept Epidemiol &

    Hlth Stat Changsha Hunan Peoples R China;

    Cent S Univ Xiangya Sch Publ Hlth Dept Epidemiol &

    Hlth Stat Changsha Hunan Peoples R China;

    Cent S Univ Xiangya Sch Publ Hlth Dept Epidemiol &

    Hlth Stat Changsha Hunan Peoples R China;

    Cent S Univ Xiangya Sch Publ Hlth Dept Epidemiol &

    Hlth Stat Changsha Hunan Peoples R China;

    Cent S Univ Xiangya Sch Publ Hlth Dept Epidemiol &

    Hlth Stat Changsha Hunan Peoples R China;

    Cent S Univ Xiangya Sch Publ Hlth Dept Epidemiol &

    Hlth Stat Changsha Hunan Peoples R China;

    Univ Ottawa Dept Obstet &

    Gynecol OMNI Res Grp Ottawa ON Canada;

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  • 原文格式 PDF
  • 正文语种 eng
  • 中图分类 毒物学(毒理学);
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