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Immune-enhancing activity of potential probiotic strains of Lactobacillus plantarum in the common carp (Cyprinus carpio) fingerling

机译:普通鲤鱼(Cyprinus carpio)鱼明中乳酸杆菌潜在益生菌菌株的免疫增强活性

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Introduction: Immune-potentiating functions of Lactobacillus plantarum strains in the common carp were evaluated. Material and Methods: Fourteen days of feeding fish dry diet supplemented with the bacteria provided parameters of non-specific humoral immunity (lysozyme, ceruloplasmin, gamma-globulin, total protein levels, and serum bactericidal activity) and cellular immunity (pinocytosis, respiratory burst activity, and potential killing activity of organ phagocytes), as well as the proliferative response of organ lymphocytes stimulated with mitogens. The resistance of fish to infection with Aeromonas hydrophila was also determined. Results: Dietary supplementation with L. plantarum had a substantial influence on the activity of organ phagocytes, especially the potential killing activity of head kidney cells. A significant increase in the proliferative activity of LPS-stimulated B lymphocytes and in the levels of gamma-globulins and total protein was observed. The supplemented diet conveyed higher resistance than the control diet as the cumulative fish mortalities after infection with A. hydrophila were 65% and 85%, respectively. Conclusion: The results indicate that dietary supplementation with L. plantarum stimulates the antibacterial resistance of common carp and may reinforce defence against bacterial infections, but further studies need to be conducted.
机译:介绍:评价钙霉菌菌株在普通鲤鱼中的免疫增强功能。材料和方法:十四天喂养鱼类干饮食补充细菌提供了非特异性体液免疫的参数(溶菌酶,刺激素,γ-球蛋白,总蛋白质水平和血清杀菌活性)和细胞免疫(吞噬症,呼吸爆发活性和器官吞噬细胞的潜在杀害活性,以及​​用丝率刺激的器官淋巴细胞的增殖反应。还测定了鱼类对感染的感染的抗性。结果:L.Playarum膳食补充剂对器官吞噬细胞的活性,尤其是头肾细胞的潜在杀伤活性的影响。观察到LPS刺激的B淋巴细胞增殖活性和在γ-球蛋白水平和总蛋白水平的显着增加。补充饮食从对照饮食传达了较高的耐受性,因为患有A.疏水液感染后的累积鱼凡人分别为65%和85%。结论:结果表明,L.Portararum的膳食补充剂刺激常见鲤鱼的抗菌性,并可加强对细菌感染的防御,但需要进行进一步的研究。

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