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首页> 外文期刊>Journal of Thermal Science and Engineering Applications: Transactions of the ASME >Three-Dimensional Numerical Study on Freezing Phase Change Heat Transfer in Biological Tissue Embedded With Two Cryoprobes
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Three-Dimensional Numerical Study on Freezing Phase Change Heat Transfer in Biological Tissue Embedded With Two Cryoprobes

机译：嵌入两个冷冻毛皮的生物组织中冷冻相变热传递的三维数值研究

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摘要

Biological tissues undergo complex phase change heat transfer processes during cryosurgery, and a theoretical model is preferable to forecast this heat experience. A mathematical model for phase change heat transfer in cryosurgery was established. In this model, a fractal treelike branched network was used to describe the complicated geometrical frame of blood vessels. The temperature distribution and ice crystal growth process in biological tissue including normal tissue and tumor embedded with two cryoprobes were numerically simulated. The effects of cooling rate, initial temperature, and distance of two cryoprobes on freezing process of tissue were also studied. The results show that the ice crystal grows more rapidly in the initial freezing stage (<600 s) and then slows down in the following process, and the precooling of cryoprobes has no obvious effect on freezing rate of tissue. It also can be seen that the distance of 10 mm between two cryoprobes produces an optimal freezing effect for the tumor size (20 mm × 10 mm) in the present study compared with the distances of 6 mm and 14 mm. The numerical results are significant in providing technical reference for application of cryosurgery in clinical medicine.
机译：生物组织在冷冻手术期间经历复杂的相变传递过程，并且理论模型是优选的预测这种热经验。建立了冷冻胶中相变热传递的数学模型。在该模型中，用于描述血管复杂的几何框架的分形轮廓分支网络。在数值模拟包括嵌入两个冷冻管的正常组织和肿瘤的生物组织中的温度分布和冰晶生长过程。还研究了冷却速率，初始温度和两个冷冻管对组织冷冻过程的影响。结果表明，冰晶在初始冻结阶段（<600秒）中迅速增长，然后在以下过程中减慢，冷冻管的预冷对组织冷冻速率没有明显影响。还可以看出，与6mm和14mm的距离相比，在本研究中，在本研究中，两个冷冻管之间的距离为肿瘤大小（20mm×10mm）的最佳冷冻效果。数值结果在为临床医学中的应用施用技术参考提供技术参考。

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