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首页> 外文期刊>Journal of women’s health >Do the Oncological and Surgical Outcomes of Young and Older Women Differ in the Treatment of Colorectal Cancer?
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Do the Oncological and Surgical Outcomes of Young and Older Women Differ in the Treatment of Colorectal Cancer?

机译：年轻和老年女性的肿瘤和手术结果是否在治疗结直肠癌？

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Background: The present study aimed to compare the surgical and oncological outcomes between young and older women with colorectal cancer (CRC). Materials and Methods: This retrospective study included 1815 women with CRC between 2010 and 2014. Participants were divided into a young group (under the age of 65 years) and an old group (65 years and older). The surgical and oncological outcomes were compared between the two groups using univariate and multivariate analyses. Results: Around 45.1% ( N = 819) patients were the older group. The old group had a higher comorbidity rate and a lower proportion of receiving postoperative chemotherapy. The old group also had a significantly higher blood loss (190 ± 611 mL vs. 145 ± 200 mL, p = 0.027) and a higher rate of intraoperative transfusion (5.4% vs. 3.0%, p = 0.011). They were found to develop more complications after surgery (11.7% vs. 7.8%, p = 0.015). The overall survival (OS) of the old group was lower than that of the young group (5-year OS rates: 72.8% vs. 83.8%, p p = 0.076). Conclusions: Older women with CRC had poorer OS than young women with CRC, but had similar CSS. Therefore, the management of comorbidities along with cancer treatment may be important in older women with CRC.
机译：背景：本研究旨在比较年轻女性与结肠直肠癌（CRC）之间的外科和肿瘤性结果。材料和方法：这项回顾性研究包括2010年和2014年之间有1815名CRC的妇女。参与者分为一个年轻的小组（在65岁以下）和旧组（65岁及以上）。使用单变量和多变量分析在两组之间比较外科和肿瘤的结果。结果：约45.1％（n = 819）患者是较旧的群体。旧组具有更高的合并率和术后化疗的较低比例。旧组还具有明显更高的血液损失（190±611ml，对145±200ml，P = 0.027）和术中输血率较高（5.4％vs.3.0％，P = 0.011）。他们被发现在手术后发育更多的并发症（11.7％vs. 7.8％，P = 0.015）。旧组的整体生存（OS）低于年轻小组（5年的OS率：72.8％vs.83.8％，P = 0.076）。结论：CRC的老年妇女比CRC的年轻女性更差，但具有类似的CSS。因此，在CRC的老年妇女中可能对癌症治疗的同血症和癌症治疗的管理可能是重要的。

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